Ahmad A, Mondal T, Klein B
Department of Pediatrics, McMaster University, ON, Canada.
Department of Pediatrics Cardiology, McMaster University, ON, Canada.
J Neonatal Perinatal Med. 2016;9(4):427-431. doi: 10.3233/NPM-160167.
Mydriatic drops are routinely administered to premature neonates to screen for retinopathy of prematurity. Adverse anticholinergic side effects, particularly convulsions and tachycardia have been reported in the pediatric age group following instillation of mydriatics for diagnostic fundus examination [1, 2]. Caffeine is frequently used for apnea of prematurity. In the neonatal intensive care unit, the combined use of caffeine and mydriatic drops is a common practice. Here we report two cases of atrial arrhythmias after neonatal eye exam that improved with conservative management. Both patients were receiving caffeine at the time of events.
常规给早产儿使用散瞳滴眼液以筛查早产儿视网膜病变。在儿科年龄组中，为进行诊断性眼底检查滴入散瞳剂后，已有抗胆碱能副作用的报道，尤其是惊厥和心动过速[1,2]。咖啡因常用于治疗早产儿呼吸暂停。在新生儿重症监护病房，联合使用咖啡因和散瞳滴眼液是常见的做法。在此，我们报告两例新生儿眼部检查后出现房性心律失常的病例，经保守治疗后病情好转。两名患者在发病时均正在使用咖啡因。
