Bozic Marija M, Karadzic Jelena B, Kovacevic Igor M, Marjanovic Ivan S
University Eye Hospital, Belgrade - Serbia.
Medical Faculty, University of Belgrade, Belgrade - Serbia.
Eur J Ophthalmol. 2017 Jun 26;27(4):481-484. doi: 10.5301/ejo.5000913. Epub 2016 Nov 28.
To assess the effect of panretinal laser photocoagulation on ocular pulse amplitude (OPA) in normotensive eyes with proliferative diabetic retinopathy.
Prospectively, we performed unilateral argon laser panretinal photocoagulation (PRP) in 30 patients with diabetes mellitus type II and previously untreated bilateral proliferative diabetic retinopathy. Before and 7 and 30 days after the treatment, OPA was measured using dynamic contour tonometer.
Compared with the untreated contralateral eyes, laser photocoagulation led to a reduction of OPA. Ocular pulse amplitude did not significantly differ in photocoagulated eyes 7 days after the treatment, but there was a significant difference in OPA 30 days after the treatment. The decrease in OPA values was 15% 7 days after PRP and 40% 30 days after PRP.
Ocular pulse amplitude reduction after PRP indirectly informs us about choriocapillary closure, already reported in previous studies.
评估全视网膜激光光凝对患有增殖性糖尿病视网膜病变的血压正常眼睛的眼脉搏振幅（OPA）的影响。
我们前瞻性地对30例II型糖尿病且之前未接受治疗的双侧增殖性糖尿病视网膜病变患者进行了单侧氩激光全视网膜光凝（PRP）。在治疗前以及治疗后7天和30天，使用动态轮廓眼压计测量OPA。
与未治疗的对侧眼相比，激光光凝导致OPA降低。治疗后7天，光凝眼的眼脉搏振幅无显著差异，但治疗后30天OPA有显著差异。PRP后7天OPA值下降15%，PRP后30天下降40%。
PRP后眼脉搏振幅降低间接告知我们脉络膜毛细血管闭合情况，这在先前的研究中已有报道。
