腰大池引流联合鞘内抗生素治疗高血压脑出血术后脑室-蛛网膜下腔感染的疗效
Efficacy of lumbar cistern drainage combined with intrathecal antibiotherapy for the treatment of ventriculo-subarachnoid infections following surgery for hypertensive intracerebral hemorrhage.
作者信息
Chen Q-H, Lin D, Yu Q-G, Zhou J
机构信息
Department of Neurosurgery, The First People's Hospital of Tonglu County, No. 338 Xuesheng Road, Hangzhou, 311500 Zhejiang, China.
Department of Neurosurgery, The First People's Hospital of Tonglu County, No. 338 Xuesheng Road, Hangzhou, 311500 Zhejiang, China.
出版信息
Neurochirurgie. 2017 Mar;63(1):13-16. doi: 10.1016/j.neuchi.2016.05.002. Epub 2016 Dec 21.
OBJECTIVE
The aim of this study was to investigate the efficacy of lumbar cistern drainage combined with intrathecal injection of antibiotics (LCD-ITI) in treating postoperative intracranial infections of hypertensive intracerebral hemorrhage (pHIH-ICI).
METHODS
Sixty pHIH-ICI patients were randomly divided into the control group and the treatment group, with 30 patients in each group. Conventional treatment was performed in the control group, while LCD-ITI was performed in the treatment group. The clinical outcomes, Glasgow Outcome Score (GOS), activities of daily living (ADL) scores, incidence rates of hydrocephalus and other indicators were compared.
RESULTS
The improvement time of clinical symptoms, infection control time and hydrocephalus incidence of the treatment group were significantly lower than the control group (P<0.05). Also the infection control rate, GOS score and ADL score of the treatment group were significantly higher or better than the control group (P<0.05).
CONCLUSION
LCD-ITI could improve clinical treatment and prognosis of pHIH-ICI patients.
目的
本研究旨在探讨腰大池引流联合鞘内注射抗生素（LCD-ITI）治疗高血压性脑出血术后颅内感染（pHIH-ICI）的疗效。
方法
将60例pHIH-ICI患者随机分为对照组和治疗组，每组30例。对照组采用常规治疗，治疗组采用LCD-ITI。比较两组的临床疗效、格拉斯哥预后评分（GOS）、日常生活活动能力（ADL）评分、脑积水发生率等指标。
结果
治疗组临床症状改善时间、感染控制时间及脑积水发生率均明显低于对照组（P<0.05）。治疗组的感染控制率、GOS评分及ADL评分也明显高于或优于对照组（P<0.05）。
结论
LCD-ITI可改善pHIH-ICI患者的临床治疗效果及预后。
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