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小脑延髓裂入路显微手术在重度脑室出血伴第四脑室铸型中的临床应用及其对神经功能恢复的影响

Clinical Application of Microsurgery Using the Cerebellar Medulla Fissure Approach in Severe Ventricular Hemorrhage with Casting of the Fourth Ventricle and Its Influence on Neurological Recovery.

作者信息

Gao Feng, Wang Huixiao, Wang Zhengzheng

机构信息

Department of Neurosurgery, The Affiliated People's Hospital of Ningbo University, Ningbo, Zhejiang 315040, China.

出版信息

Evid Based Complement Alternat Med. 2021 Oct 25;2021:3699233. doi: 10.1155/2021/3699233. eCollection 2021.

Abstract

OBJECTIVE

To investigate the clinical application of microsurgery using the cerebellar medulla fissure approach in severe ventricular hemorrhage with casting of the fourth ventricle and its effect on neurological recovery.

METHODS

A total of 80 patients with severe intraventricular hemorrhage accompanied by casting and dilation of the fourth ventricle who were admitted to the neurosurgery department between July 2019 and December 2020 were randomly divided into an observation group and a control group, with 40 patients in each group. The drainage tube extubation time and length of hospital stay of the two groups were compared. The 3-day hematoma clearance of the two groups was observed. Postoperative consciousness was evaluated by GCS, and the patients' recovery was evaluated by GOS at three months. The activities of daily living (ADL) scores of the two groups were compared to evaluate patients' postoperative self-care ability. The incidence of postoperative complications in the two groups was collected. Independent risk factors for poor prognosis were analyzed by logistics regression.

RESULTS

The postoperative hospitalization time and the drainage tube extubation time in the observation group were significantly lower than those in the control group. The ratio of hematoma clearance ≥90% in the observation group was significantly higher than that of the control group. Postoperative GCS scores and GOS scores in the observation group were significantly higher than those of the control group. The rate of postoperative complications in the observation group was significantly lower than that of the control group. The rate of good ADL grading in the observation group was significantly higher than that in the control group. Age and surgical method were independent risk factors for poor prognosis.

CONCLUSION

Microsurgery using the cerebellar medulla fissure approach can effectively improve the condition of severe ventricular hemorrhage with casting of the fourth ventricle and promote the recovery of patients' neurological function.

摘要

目的

探讨采用小脑延髓裂入路显微手术治疗重度脑室出血伴第四脑室铸型的临床应用及其对神经功能恢复的影响。

方法

选取2019年7月至2020年12月神经外科收治的80例重度脑室出血伴第四脑室铸型及扩张患者,随机分为观察组和对照组,每组40例。比较两组的引流管拔除时间和住院时间。观察两组术后3天的血肿清除情况。采用格拉斯哥昏迷量表(GCS)评估术后意识,术后3个月采用格拉斯哥预后量表(GOS)评估患者恢复情况。比较两组的日常生活活动能力(ADL)评分,以评估患者术后的自我护理能力。收集两组术后并发症的发生率。通过logistic回归分析预后不良的独立危险因素。

结果

观察组术后住院时间和引流管拔除时间均显著低于对照组。观察组血肿清除率≥90%的比例显著高于对照组。观察组术后GCS评分和GOS评分均显著高于对照组。观察组术后并发症发生率显著低于对照组。观察组ADL分级良好率显著高于对照组。年龄和手术方式是预后不良的独立危险因素。

结论

采用小脑延髓裂入路显微手术可有效改善重度脑室出血伴第四脑室铸型患者的病情,促进患者神经功能恢复。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/32a5/8560247/90f9f496ae35/ECAM2021-3699233.001.jpg

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