Liao S X, Han G Y, Zhang Y R, Zheng Q T, He C H
Yao Xue Xue Bao. 1989;24(2):110-3.
Desmos cochinchinensis as a folk medicine is used for treatment of malaria in China. Pharmacological studies showed that the petroleum ether extract of the root of the plant exhibited anti-malarial activity. Three flavonoids were isolated from this extract, of which two were identified as lawinal and isounonal. Compound III is a new flavanol. On the basis of spectroscopic analyses (UV, IR, MS, 1HNMR, 13CNMR and X-RD) the structure was established as 4,7-dihydroxyl-5-methoxyl-6-methyl-8-formyl-flavan. I and II were found from this plant for the first time.
毛叶黄檀作为一种民间药物在中国用于治疗疟疾。药理学研究表明，该植物根的石油醚提取物具有抗疟活性。从该提取物中分离出三种黄酮类化合物，其中两种被鉴定为拉维纳尔和异乌纳尔。化合物III是一种新的黄烷醇。基于光谱分析（紫外、红外、质谱、1H核磁共振、13C核磁共振和X射线衍射），其结构被确定为4,7 - 二羟基 - 5 - 甲氧基 - 6 - 甲基 - 8 - 甲酰基 - 黄烷。化合物I和II首次从该植物中发现。
