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[滇黄芩根中新黄酮类化合物的结构研究]

[Studies on the structures of new flavonoids from the root of Scutellaria amoena].

作者信息

Hu B H, Liu Y L

出版信息

Yao Xue Xue Bao. 1989;24(3):200-6.

PMID:2816376
Abstract

From the root of Scutellaria amoena C.H. Wright, two new flavonoids (I, II) and six known flavonoids (III-VIII) were isolated. On the basis of spectroscopic analysis (UV, 1HNMR, 13CNMR, MS and CD) and chemical evidences, the structures of I and II were elucidated as (2S)-2',5,6'-trihydroxy-7-methoxyflavanone-2'-O-beta-D-glucopyrano side (I) and (2R, 3R)-2',3,5,7-tetrahydroxyflavanone (II) respectively. The other six known compounds were identified as (2S)-5,7,8-trihydroxyflavanone (III), (2S)-2',5,6',7-tetrahydroxyflavanone (IV), (2R, 3R)-2',3,5,6',7-pentahydroxyflavanone (V), 2',5,6',7-tetrahydroxyflavone (VI) norwogonin (VII) and oroxylin-A (VIII) respectively. Compounds III-VIII were obtained from this plant for the first time.

摘要

从滇黄芩(Scutellaria amoena C.H. Wright)的根中分离得到了两个新的黄酮类化合物(I、II)和六个已知的黄酮类化合物(III - VIII)。基于光谱分析(紫外光谱、1H核磁共振、13C核磁共振、质谱和圆二色光谱)以及化学证据,化合物I和II的结构分别被鉴定为(2S)-2',5,6'-三羟基-7-甲氧基黄烷酮-2'-O-β-D-吡喃葡萄糖苷(I)和(2R, 3R)-2',3,5,7-四羟基黄烷酮(II)。另外六个已知化合物分别被鉴定为(2S)-5,7,8-三羟基黄烷酮(III)、(2S)-2',5,6',7-四羟基黄烷酮(IV)、(2R, 3R)-2',3,5,6',7-五羟基黄烷酮(V)、2',5,6',7-四羟基黄酮(VI)、去甲汉黄芩素(VII)和木犀草素A(VIII)。化合物III - VIII首次从该植物中获得。

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