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Reduction of aGVHD using chicken antibodies directed against intestinal pathogens in a murine model.

作者信息

Bouazzaoui Abdellatif, Huber Elisabeth, Dan Alexander, Al-Allaf Faisal A, Pfirstinger Jochen, Sprotte Günter, Köstler Josef, Hiergeist Andreas, Gessner Andre, Herr Wolfgang, Holler Ernst

机构信息

Medical Clinic 3-Hematology/Oncology, University Hospital Regensburg, Regensburg, Germany.

Science and Technology Unit and.

出版信息

Blood. 2017 Feb 23;129(8):1052-1055. doi: 10.1182/blood-2016-06-722538. Epub 2016 Dec 23.

DOI:10.1182/blood-2016-06-722538
PMID:28011676
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5335808/
Abstract
摘要

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本文引用的文献

1
Role of gut flora after bone marrow transplantation.骨髓移植后肠道菌群的作用。
Nat Microbiol. 2016 Mar 29;1:16036. doi: 10.1038/nmicrobiol.2016.36.
2
Increased GVHD-related mortality with broad-spectrum antibiotic use after allogeneic hematopoietic stem cell transplantation in human patients and mice.在人类患者和小鼠接受异基因造血干细胞移植后，使用广谱抗生素会增加移植物抗宿主病（GVHD）相关死亡率。
Sci Transl Med. 2016 May 18;8(339):339ra71. doi: 10.1126/scitranslmed.aaf2311.
3
Akkermansia Muciniphila Protects Against Atherosclerosis by Preventing Metabolic Endotoxemia-Induced Inflammation in Apoe-/- Mice.阿克曼氏菌（Akkermansia muciniphila）通过预防载脂蛋白 E 基因敲除（Apoe-/-）小鼠的代谢性内毒素血症诱导的炎症来预防动脉粥样硬化。
Circulation. 2016 Jun 14;133(24):2434-46. doi: 10.1161/CIRCULATIONAHA.115.019645. Epub 2016 Apr 25.
4
Protective effects of chicken egg yolk antibody (IgY) against experimental Vibrio splendidus infection in the sea cucumber (Apostichopus japonicus).鸡蛋黄抗体（IgY）对实验性灿烂弧菌感染海参（刺参）的保护作用。
Fish Shellfish Immunol. 2016 Jan;48:105-11. doi: 10.1016/j.fsi.2015.11.024. Epub 2015 Nov 22.
5
Intestinal Blautia Is Associated with Reduced Death from Graft-versus-Host Disease.肠道布劳特氏菌与移植物抗宿主病死亡风险降低有关。
Biol Blood Marrow Transplant. 2015 Aug;21(8):1373-83. doi: 10.1016/j.bbmt.2015.04.016. Epub 2015 May 11.
6
The effects of intestinal tract bacterial diversity on mortality following allogeneic hematopoietic stem cell transplantation.异基因造血干细胞移植后肠道细菌多样性对死亡率的影响。
Blood. 2014 Aug 14;124(7):1174-82. doi: 10.1182/blood-2014-02-554725. Epub 2014 Jun 17.
7
Cytostatic conditioning in experimental allogeneic bone marrow transplantation: Busulfan causes less early gastrointestinal toxicity but Treosulfan results in improved immune reconstitution.实验性异基因骨髓移植中的细胞抑制预处理：白消安导致的早期胃肠道毒性较小，但曲奥舒凡可改善免疫重建。
Immunopharmacol Immunotoxicol. 2014 Apr;36(2):158-64. doi: 10.3109/08923973.2014.895743. Epub 2014 Mar 4.
8
Metagenomic analysis of the stool microbiome in patients receiving allogeneic stem cell transplantation: loss of diversity is associated with use of systemic antibiotics and more pronounced in gastrointestinal graft-versus-host disease.接受异基因干细胞移植患者粪便微生物组的宏基因组分析：多样性丧失与全身使用抗生素有关，且在胃肠道移植物抗宿主病中更为明显。
Biol Blood Marrow Transplant. 2014 May;20(5):640-5. doi: 10.1016/j.bbmt.2014.01.030. Epub 2014 Jan 31.
9
Oral passive IgY-based immunotherapeutics: a novel solution for prevention and treatment of alimentary tract diseases.口服被动免疫 IgY 治疗剂：预防和治疗消化道疾病的新方法。
Hum Vaccin Immunother. 2013 May;9(5):1039-48. doi: 10.4161/hv.23383. Epub 2013 Jan 14.
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IgY antibodies protect against human Rotavirus induced diarrhea in the neonatal gnotobiotic piglet disease model.IgY 抗体可预防新生无菌仔猪疾病模型中人类轮状病毒引起的腹泻。
PLoS One. 2012;7(8):e42788. doi: 10.1371/journal.pone.0042788. Epub 2012 Aug 3.