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[意大利两家三级医院的输入性登革热:快速诊断检测的应用]

[Imported dengue in two tertiary Italian hospitals: Use of rapid diagnostic tests].

作者信息

Calleri G, Torta I, Gobbi F, Angheben A, Lipani F, Lucchini A, Burdino E, Ghisetti V, Caramello P

机构信息

Travel Medicine Unit, Amedeo di Savoia Hospital, Torino, Italy.

Centre for Tropical Diseases, Sacro Cuore-Don Calabria Hospital, Negrar-Verona, Italy.

出版信息

Bull Soc Pathol Exot. 2017 Feb;110(1):13-19. doi: 10.1007/s13149-017-0542-x. Epub 2016 Dec 23.

DOI:10.1007/s13149-017-0542-x
PMID:28012140
Abstract

Dengue fever is growing at a global level both as number of cases and as geographic area of endemicity. Italy is not in endemic area, but the competent vector Aedes albopictus is widespread in this country, so that the possibility of introduction of the infection cannot be ruled out. We retrospectively collected demographic, clinical, and laboratory data about consecutive cases diagnosed in Torino and Negrar-Verona in the period 2010-2015. One hundred thirteen cases of dengue were observed, with an increasing trend during years. The infection was imported mostly from south-east Asia, but the risk appears to be higher in Latin America. More than half of the patients were admitted to the hospital but only one case of severe dengue was observed. Many patients presented after the resolution of symptoms. Rapid diagnostic tests were done in the majority of patients and allowed a diagnosis both in the acute (NS1 antigen) and convalescent (IgMantibodies) phases of the disease. An early diagnosis is paramount to avoid the spreading of the infection.

摘要

登革热在全球范围内,无论是病例数量还是流行地区都在不断增加。意大利并非登革热流行地区,但主要病媒白纹伊蚊在该国广泛分布,因此不能排除引入该感染的可能性。我们回顾性收集了2010年至2015年期间在都灵和内格拉尔 - 维罗纳诊断的连续病例的人口统计学、临床和实验室数据。共观察到113例登革热病例,且病例数呈逐年上升趋势。感染大多从东南亚输入,但在拉丁美洲风险似乎更高。超过一半的患者住院治疗,但仅观察到1例重症登革热病例。许多患者在症状缓解后才前来就诊。大多数患者进行了快速诊断检测,在疾病的急性期(NS1抗原)和恢复期(IgM抗体)均能做出诊断。早期诊断对于避免感染传播至关重要。

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引用本文的文献

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Imported Dengue Fever in Milan, Italy: A Seven-Year Retrospective Study.意大利米兰的输入性登革热:一项七年回顾性研究。
Infect Dis Rep. 2025 Sep 12;17(5):113. doi: 10.3390/idr17050113.
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Dengue Fever in Italy: The "Eternal Return" of an Emerging Arboviral Disease.意大利的登革热:一种新发虫媒病毒病的“再度流行”
Trop Med Infect Dis. 2022 Jan 13;7(1):10. doi: 10.3390/tropicalmed7010010.