致癌性低磷性骨软化症：从疾病的首个信号到健康的首个信号。

Oncogenic hypophosphatemic osteomalacia: From the first signal of disease to the first signal of healthy.

作者信息

Gatti Arthur Paredes, Tonello Luiza, Neto João Alfredo Diedrich, Teixeira Uirá Fernandes, Goldoni Marcos Bertozzi, Fontes Paulo Roberto Ott, Sampaio José Artur, Lima Luiz Maraninchi Pereira, Waechter Fábio Luiz

机构信息

General Surgery Unit, Universidade Federal De Ciências Da Saúde De Porto Alegre, Complexo Hospitalar Santa Casa de Porto Alegre, Porto Alegre, RS 90050-170, Brazil.

出版信息

Int J Surg Case Rep. 2017;30:130-133. doi: 10.1016/j.ijscr.2016.11.037. Epub 2016 Nov 27.

DOI:10.1016/j.ijscr.2016.11.037

PMID:28012328

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC5192016/

Abstract

INTRODUCTION

The physical incapacitation of the oncogenic hypophosphatemic osteomalacia (OHO) can be catastrophic and can lead to deformities, metabolic and organic instability and death. The only positive outcome is through early diagnosis by the clinical suspicion. At this moment, medical center infrastructure is also a keypoint.

PRESENTATION OF CASE

This case report is about a 60-year old woman with multiple fractures, gradual loss of strength and muscle mass and limiting deformities in two years of evolution until the diagnostic.

DISCUSSION

The lack of knowledge of this disease causes a delay in diagnosis that can bring deformities to the patient, as well as death. Is crucial that is hypothesized to carry out the necessary tests, since they are expensive and not always available.

CONCLUSION

This case reinforces the importance to understand the OHO and tumoral search, once this lesion is, in most cases, imperceptible to physical examination or several imaging studies.

摘要