Dhammi Ish K, Jain Anil K, Singh Ajay Pal, Mishra Puneet, Jain Saurabh
Department of Orthopedics, UCMS and GTB Hospital, Delhi, India.
Indian J Orthop. 2010 Oct;44(4):453-7. doi: 10.4103/0019-5413.69320.
Oncogenic osteomalacia is a rare association between mesenchymal tumors and hypophosphatemic rickets. It is more of a biochemical entity than a clinical one. The pathophysiology of the tumor is not clear. However, it has been seen that the clinical and biochemical parameters become normal if the lesion responsible for producing the osteomalacia is excised. For a clinical diagnosis a high index of suspicion is necessary. We present three such cases where in one the oncogenic osteomalacia reversed while in rest it did not. We present this case report to sensitize about the entity.
致癌性骨软化症是一种间充质肿瘤与低磷血症性佝偻病之间的罕见关联。与其说它是一种临床病症，不如说是一种生化实体。肿瘤的病理生理学尚不清楚。然而，已经观察到，如果切除导致骨软化症的病变，临床和生化参数会恢复正常。临床诊断需要高度的怀疑指数。我们报告三例这样的病例，其中一例致癌性骨软化症得到逆转，而其余病例未逆转。我们呈现此病例报告以提高对该病症的认识。
