Gonzalez Della Valle Alejandro, Blanes Perez Alvaro, Lee Yuo-Yu, Saboeiro Gregory R, Konin Gabrielle P, Endo Yoshimi, Sharrock Nigel E, Salvati Eduardo A
Hospital for Special Surgery, Weill Medical College of Cornell University, New York, New York.
J Arthroplasty. 2017 Apr;32(4):1304-1309. doi: 10.1016/j.arth.2016.11.023. Epub 2016 Nov 25.
In the event of a postoperative pulmonary embolism (PE), it is generally believed that patients with centrally located emboli will have worse clinical symptoms than those with segmental or subsegmental ones. We studied if a relationship exists between the clinical severity at the time of PE diagnosis and the location of the emboli within the pulmonary vasculature.
All 269 patients who developed an in-hospital, computed tomography pulmonary angiography-proved, PE following elective total hip arthroplasty or total knee arthroplasty in our institution were studied. The clinical severity of the PE was calculated using the Pulmonary Embolism Severity Index (PESI) that classifies patients in 5 classes (class 5: most severe). All computed tomography pulmonary angiographies were re-reviewed to determine the location of the emboli within the pulmonary vasculature (central, segmental, or subsegmental-unilateral or bilateral). The association between PESI and the PE location was examined.
The most proximal location of the emboli was central in 62, segmental in 139, and subsegmental in 68. There were 180 unilateral and 89 bilateral PE patients. There was no association between the PESI and the location of the emboli within the pulmonary vasculature (P = .32). Patients with bilateral or unilateral lung involvement had similar PESI (P = .78).
The PESI, a recognized, validated predictor of mortality after PE was similar in patients with central, segmental, or subsegmental PE; and in patients with unilateral or bilateral lung involvement. The present study may aid clinicians while assessing and discussing the severity of PE symptoms with patients at the time of diagnosis.
在术后发生肺栓塞(PE)的情况下,一般认为中心型栓塞患者的临床症状比节段性或亚段性栓塞患者更严重。我们研究了PE诊断时的临床严重程度与肺血管内栓子位置之间是否存在关联。
对我院因择期全髋关节置换术或全膝关节置换术住院且经计算机断层扫描肺动脉造影证实发生PE的269例患者进行了研究。使用肺栓塞严重程度指数(PESI)计算PE的临床严重程度,该指数将患者分为5类(5类:最严重)。对所有计算机断层扫描肺动脉造影进行重新评估,以确定肺血管内栓子的位置(中心型、节段性或亚段性——单侧或双侧)。检查了PESI与PE位置之间的关联。
栓子最近端的位置为中心型62例,节段性139例,亚段性68例。有180例单侧PE患者和89例双侧PE患者。PESI与肺血管内栓子位置之间无关联(P = 0.32)。双侧或单侧肺受累的患者PESI相似(P = 0.78)。
PESI是一种公认的、经过验证的PE后死亡率预测指标,在中心型、节段性或亚段性PE患者以及单侧或双侧肺受累的患者中相似。本研究可能有助于临床医生在诊断时与患者评估和讨论PE症状的严重程度时提供帮助。