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11 年间 11249 例下肢关节置换术后 CT 肺动脉造影:回顾性研究。

CT pulmonary angiography in lower limb arthroplasty: A retrospective review of 11 249 patients over 11 years.

机构信息

Musgrave Park Hospital, Belfast, UK.

Musgrave Park Hospital, Belfast, Co. Antrim, UK.

出版信息

Bone Joint J. 2018 Jul;100-B(7):938-944. doi: 10.1302/0301-620X.100B7.BJJ-2017-1239.R4.

Abstract

AIMS

The aims of this study were to determine the indications and frequency of ordering a CT pulmonary angiography (CTPA) following primary arthroplasty of the hip and knee, and to determine the number of positive scans in these patients, the location of emboli and the outcome for patients undergoing CTPA.

PATIENTS AND METHODS

We analyzed the use of CTPA, as an inpatient and up to 90 days as an outpatient, in a cohort of patients and reviewed the medical records and imaging for each patient undergoing CTPA.

RESULTS

Out of 11 249 patients, scans were requested in 229 (2.04%) and 86 (38%) were positive. No patient undergoing CTPA died within 90 days. The rate of mortality from pulmonary embolism (PE) overall was 0.08%. CTPA was performed twice as often following total knee arthroplasty (TKA) compared with total hip arthroplasty (THA), and when performed was twice as likely to be positive. Hypoxia was the main indication for a scan, being the indication in 149 scans (65%); and in 23% (11 of 47), the PE was peripheral and unilateral. Three patients suffered complications resulting from therapeutic anticoagulation for possible PE, two of whom had a negative CTPA.

CONCLUSION

CTPA is more likely to be performed following TKA compared with THA. Hypoxia was the main presenting feature of PE. A quarter of PEs which were diagnosed were unilateral and peripheral. Further study may indicate which patients who have a PE after lower limb arthroplasty require treatment, and which can avoid the complications associated with anticoagulation. Cite this article: Bone Joint J 2018;100-B:938-44.

摘要

目的

本研究旨在确定髋关节和膝关节初次置换术后行 CT 肺动脉造影(CTPA)的适应证和频率,并确定这些患者中阳性扫描的数量、栓子的位置以及行 CTPA 患者的结局。

患者和方法

我们分析了一组患者住院期间和出院后 90 天内行 CTPA 的情况,并对每位行 CTPA 的患者的病历和影像学资料进行了回顾。

结果

在 11249 例患者中,229 例(2.04%)行 CTPA 检查,其中 86 例(38%)为阳性。在 90 天内,无患者因肺栓塞(PE)死亡。PE 的总体死亡率为 0.08%。与全髋关节置换术(THA)相比,全膝关节置换术(TKA)后行 CTPA 的比例增加了一倍,且行 CTPA 的阳性率也增加了一倍。缺氧是行 CTPA 的主要指征,占 149 次扫描的 65%;23%(47 例中的 11 例)为外周性和单侧性 PE。3 例患者因可能的 PE 行抗凝治疗出现并发症,其中 2 例 CTPA 结果为阴性。

结论

与 THA 相比,TKA 后更可能行 CTPA。缺氧是 PE 的主要表现。诊断出的四分之一的 PE 为单侧和外周性。进一步的研究可能表明,哪些下肢关节置换术后出现 PE 的患者需要治疗,哪些患者可以避免与抗凝相关的并发症。

文献出处

Bone Joint J 2018;100-B:938-44.

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