Division of Vascular Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Division of Vascular Surgery, Department of Surgery, The University of Hong Kong, Queen Mary Hospital, Hong Kong.
Asian J Surg. 2018 Mar;41(2):176-182. doi: 10.1016/j.asjsur.2016.11.005. Epub 2016 Dec 22.
BACKGROUND/OBJECTIVE: Deep vein thrombosis (DVT) was thought to be uncommon in Asians and routine thromboprophylaxis in the form of anticoagulation for surgical patients was considered to be unnecessary. The current study aims to provide a contemporary epidemiology of venous thromboembolism in a population-based scale.
Information from January 1, 2010 to December 31, 2011 was retrieved from a centralized computer public healthcare database serving mainly an ethnic Han Chinese population of 7.1 million. The incidence, demographics, and hospital mortality rates of DVT and pulmonary embolism (PE) were obtained, and analyzed for different surgical categories.
The overall annual incidences of DVT, PE alone, and PE with DVT were 30.0 per 100,000 population, 8.7 per 100,000 population, and 3.0 per 100,000 population, respectively. Overall male to female ratio was 1:1.24. Venous thromboembolic disease was more common with increasing age in both sexes. Thirty days' mortality rates associated with DVT, PE alone, and PE with DVT were 9.0%, 17.4%, and 13.3% respectively. Among the patients who received 103,023 major and intermediate surgical procedures in the study period, the mean incidence of postoperative DVT, PE alone, and PE with DVT were only 0.20% (203.5 patients), 0.08% (85.5 patients), and 0.04% (40.5 patients) respectively.
Compared with a similar study 10 years ago, there seemed to be a general increase in incidence of DVT and PE. This study showed that postoperative thromboembolic events were not uncommon, with DVT occurring in up to 0.2% of patients and PE in 0.12% of patients in this longitudinal survey.
背景/目的：深静脉血栓形成（DVT）在亚洲人群中较为少见，因此认为手术患者常规抗凝预防血栓形成没有必要。本研究旨在提供基于人群的静脉血栓栓塞症的当代流行病学资料。
从一个为主要汉族人口（710 万）服务的集中式计算机公共医疗数据库中检索了 2010 年 1 月 1 日至 2011 年 12 月 31 日的信息。获得了 DVT 和肺栓塞（PE）的发病率、人口统计学和住院死亡率，并对不同手术类别进行了分析。
DVT、单纯性 PE 和 DVT 合并 PE 的年总发病率分别为 30.0/10 万、8.7/10 万和 3.0/10 万。总体男女比例为 1:1.24。静脉血栓栓塞性疾病在男女两性中均随年龄增长而更为常见。DVT、单纯性 PE 和 DVT 合并 PE 的 30 天死亡率分别为 9.0%、17.4%和 13.3%。在研究期间接受了 103023 例大、中型手术的患者中，术后 DVT、单纯性 PE 和 DVT 合并 PE 的平均发病率分别仅为 0.20%（203.5 例）、0.08%（85.5 例）和 0.04%（40.5 例）。
与 10 年前的一项类似研究相比，DVT 和 PE 的发病率似乎普遍有所增加。本研究表明，术后血栓栓塞事件并不少见，在这项纵向研究中，DVT 的发生率高达 0.2%，PE 的发生率为 0.12%。
