de Jonge M, Dekker J J M, Kikkert M J, Peen J, van Rijsbergen G D, Bockting C L H
Department of Research Arkin, Amsterdam, The Netherlands.
Department of Research Arkin, Amsterdam, The Netherlands; Department of Clinical Psychology, Vrije Universiteit, Amsterdam, The Netherlands.
J Affect Disord. 2017 Mar 1;210:66-71. doi: 10.1016/j.jad.2016.12.015. Epub 2016 Dec 18.
Major depressive disorder is an emotional disorder. It is important to improve our understanding of the role of affect in relapse/recurrence of depression. Therefore, this study examines whether affect plays a role in prospectively predicting depressive symptomatology and if there are indications for emotional scarring as a consequence of undergoing depressive episodes.
In 107 patients remitted from recurrent depression affect was examined in predicting depressive symptomatology as measured with the Inventory of Depressive Symptomatology - Self Report. Affect was measured with the Positive and Negative Affect Schedule and with a one item Visual Analogue Mood Scale. Indication of emotional scarring was examined by comparing number of previous depressive episodes to levels of affect.
Less positive affect as assessed after remission predicted increased depressive symptomatology six months later, even after we controlled for baseline symptomatology. Negative affect also predicted depressive symptomatology six months later, but not after controlling for baseline depressive symptomatology. No relationship was found between affect and number of previous episodes.
All participants in this study had two or more previous depressive episodes and received CBT during the acute phase of their depression. The instruments that measured mood and affect were administered within 4 weeks of each other.
Positive affect and negative affect as assessed after remission in recurrent depression can predict depressive symptomatology. Especially positive affect seems to play an independent role in predicting depressive symptomatology. Directly targeting positive affect in relapse prevention during remission might be a way to enhance treatment effects.
重度抑郁症是一种情绪障碍。增进我们对情感在抑郁症复发/再发中作用的理解非常重要。因此，本研究探讨情感是否在预测抑郁症状方面发挥前瞻性作用，以及是否有迹象表明经历抑郁发作会导致情感创伤。
对107例复发性抑郁症缓解期患者，通过抑郁症状量表-自评版来检测情感在预测抑郁症状方面的作用。情感通过正负性情绪量表和单项视觉模拟情绪量表进行测量。通过比较既往抑郁发作次数与情感水平来检测情感创伤迹象。
缓解期后评估的积极情感较少，即使在我们控制了基线症状后，仍可预测六个月后抑郁症状增加。消极情感也可预测六个月后的抑郁症状，但在控制了基线抑郁症状后则不然。未发现情感与既往发作次数之间存在关联。
本研究所有参与者既往均有两次或更多次抑郁发作，且在抑郁症急性期接受了认知行为疗法。测量情绪和情感的工具在彼此4周内进行施测。
复发性抑郁症缓解期评估的积极情感和消极情感可预测抑郁症状。尤其是积极情感似乎在预测抑郁症状方面发挥独立作用。在缓解期预防复发时直接针对积极情感可能是增强治疗效果的一种方法。
