Ata-Lawenko Rona M, Lee Yeong Yeh
Section of Gastroenterology, De La Salle Health Sciences Institute, Dasmarinas City, Cavite, Philippines.
School of Medical Sciences, Universiti Sains Malaysia, Kubang Kerian, Kota Bahru, Kelantan, Malaysia.
J Neurogastroenterol Motil. 2017 Apr 30;23(2):164-170. doi: 10.5056/jnm16171.
Gastrointestinal sphincters play a vital role in gut function and motility by separating the gut into functional segments. Traditionally, function of sphincters including the esophagogastric junction is studied using endoscopy and manometry. However, due to its dynamic biomechanical properties, data on distensibility and compliance may provide a more accurate representation of the sphincter function. The endolumenal functional lumen imaging probe (EndoFLIP) system uses a multi-detector impedance planimetry system to provide data on tissue distensibility and geometric changes in the sphincter as measured through resistance to volumetric distention with real-time images. With the advent of EndoFLIP studies, esophagogastric junction dysfunction and other disorders of the stomach and bowels may be better evaluated. It may be utilized as a tool in predicting effectiveness of endoscopic and surgical treatments as well as patient outcomes.
胃肠括约肌通过将肠道分隔成不同功能段，在肠道功能和蠕动中发挥着至关重要的作用。传统上，包括食管胃交界处在内的括约肌功能是通过内镜检查和测压法来研究的。然而，由于其动态生物力学特性，关于扩张性和顺应性的数据可能会更准确地反映括约肌功能。腔内功能性管腔成像探头（EndoFLIP）系统使用多探测器阻抗平面测量系统，通过实时图像测量括约肌对容积扩张的阻力，从而提供有关组织扩张性和几何变化的数据。随着EndoFLIP研究的出现，食管胃交界处功能障碍以及其他胃肠疾病可能会得到更好的评估。它可作为一种工具，用于预测内镜和手术治疗的效果以及患者的预后。
