White Emily, Mutalib Mohamed
Department of Paediatric Gastroenterology, Evelina London Children's Hospital, London SE1 7EH, United Kingdom.
Faculty of Life Sciences and Medicine, King's College London, London SE1 7EH, United Kingdom.
World J Clin Pediatr. 2023 Sep 9;12(4):162-170. doi: 10.5409/wjcp.v12.i4.162.
Investigating gastrointestinal (GI) motility disorders relies on diagnostic tools to assess muscular contractions, peristalsis propagation and the integrity and coordination of various sphincters. Manometries are the gold standard to study the GI motor function but it is increasingly acknowledged that manometries do not provide a complete picture in relation to sphincters competencies and muscle fibrosis. Endolumenal functional lumen imaging probe (EndoFLIP) an emerging technology, uses impedance planimetry to measure hollow organs cross sectional area, distensibility and compliance. It has been successfully used as a complementary tool in the assessment of the upper and lower oesophageal sphincters, oesophageal body, the pylorus and the anal canal. In this article, we aim to review the uses of EndoFLIP as a tool to investigate GI motility disorders with a special focus on paediatric practice. The majority of EndoFLIP studies were conducted in adult patients but the uptake of the technology in paediatrics is increasing. EndoFLIP can provide a useful complementary data to the existing GI motility investigation in both children and adults.
研究胃肠道（GI）动力障碍依赖于诊断工具来评估肌肉收缩、蠕动传播以及各种括约肌的完整性和协调性。测压法是研究胃肠运动功能的金标准，但人们越来越认识到，测压法并不能全面反映括约肌功能和肌肉纤维化情况。腔内功能性管腔成像探头（EndoFLIP）是一项新兴技术，它利用阻抗平面测量法来测量中空器官的横截面积、扩张性和顺应性。它已成功用作评估食管上下括约肌、食管体、幽门和肛管的辅助工具。在本文中，我们旨在综述EndoFLIP作为一种研究胃肠动力障碍的工具的用途，特别关注儿科应用。大多数EndoFLIP研究是在成年患者中进行的，但该技术在儿科的应用正在增加。EndoFLIP可以为儿童和成人现有的胃肠动力研究提供有用的补充数据。
