Watanabe K, Yuri K
Department of Urology, Saiseikai Kyoto University.
Hinyokika Kiyo. 1989 May;35(5):769-73.
The effects of Urocalun and jumping exercise upon the passage of calculi were studied. Urocalun was administered to 47 patients with ureteral stones in a dosage of 6 capsules per day and they did jumping rope skipping 50 times twice a day. The size of the calculi was grouped according to the report of Minami et al. Namely the 47 cases were divided into the following groups according to their radiographic shadow; 1) small group (not greater than 0.5 cm in diameter), 27 cases (57.4%); 2) middle-sized group (not greater than 1.0 x 0.6 cm), 11 cases (23.4%); 3) large group (larger than 1.0 x 0.6 cm), 9 cases (19.2%). As a result, the rate of spontaneous passage was 80.9% which was considerably higher than expected. There was spontaneous passage of calculus in 25 cases of small group (85.2%), in 8 cases of middle-sized group (72.7%) and in 7 cases of large group (77.8%). Especially in the large group the rate of passage was higher than described before. On the other hand the period of calculi passage was earlier than that in Minami's report. In the large group 6 of the 7 discharged stones (85.7%) were discharged within six months. Therefore, it must be observed for six months regardless of calculus size with combination therapy if possible. The effects of this prescription on the calculi passage were better than those described on other drugs and Urocalun independently. Then the strict combination therapy of the drug and the exercise was useful for the passage of calculi.
研究了消石素和跳跃运动对结石排出的影响。对47例输尿管结石患者给予消石素，剂量为每日6粒胶囊，他们每天跳绳50次，分两次进行。根据南波等人的报告对结石大小进行分组。具体而言，这47例患者根据其X线影像分为以下几组：1）小结石组（直径不大于0.5 cm），27例（57.4%）；2）中结石组（不大于1.0×0.6 cm），11例（23.4%）；3）大结石组（大于1.0×0.6 cm），9例（19.2%）。结果，自然排出率为80.9%，大大高于预期。小结石组25例（85.2%）结石自然排出，中结石组8例（72.7%），大结石组7例（77.8%）。特别是大结石组的排出率高于之前报道。另一方面，结石排出的时间比南波报告中的更早。大结石组7例排出结石中有6例（85.7%）在6个月内排出。因此，如果可能的话，无论结石大小，联合治疗都必须观察6个月。该处方对结石排出的效果优于其他药物及单独使用消石素的效果。因此，药物与运动的严格联合治疗对结石排出是有效的。
