Brooks B S, el Gammal T, Allison J D, Hoffman W H
Department of Radiology, Medical College of Georgia, Augusta 30912.
AJR Am J Roentgenol. 1989 Nov;153(5):1033-8. doi: 10.2214/ajr.153.5.1033.
Sagittal T1-weighted series with 3-mm sections have routinely been used for all cranial MR studies at our institution. It was apparent from examining these studies that the rate of occurrence of a normal posterior pituitary bright signal was lower than has been previously reported, particularly in older patients. This prompted both a retrospective and a prospective review and analysis of the posterior lobe bright signal in three patient categories. The overall frequency of posterior pituitary bright signal and the influence of sex and age were evaluated in one category. An age-related statistically significant decline in the frequency of posterior pituitary bright signal was found, with a decline rate of approximately 1% per year. An evaluation of the occurrence of anatomic variation in the location of posterior lobe bright signal was made in a second group of 1500 patients. Abberrant location of the posterior lobe was found to be uncommon and was seen most frequently in patients with a sellar fossula. Temporal variation in the presence or absence and size of the posterior lobe bright signal was evaluated in a third group of 36 patients who had at least two MR examinations available for review. Follow-up MR study showed an obvious posterior lobe bright signal in 8% of these patients for whom no bright signal was apparent at the time of initial examination. Loss of the posterior lobe bright signal was apparent in another 25% of patients. A significant change in size of the bright signal was apparent in 19% of patients within this category. Our results indicate that variation in the bright signal of the posterior pituitary lobe should be expected as a normal physiological occurrence.
在我们机构，矢状位T1加权序列（层厚3毫米）常规用于所有颅脑磁共振成像研究。从这些研究中可以明显看出，正常垂体后叶高信号的发生率低于先前报道，尤其是在老年患者中。这促使我们对三类患者的垂体后叶高信号进行回顾性和前瞻性的审查与分析。在一类患者中评估了垂体后叶高信号的总体频率以及性别和年龄的影响。发现垂体后叶高信号频率随年龄有统计学意义的下降，每年下降率约为1%。在另一组1500例患者中评估了垂体后叶高信号位置的解剖变异发生率。发现垂体后叶位置异常并不常见，最常见于蝶鞍小凹患者。在第三组36例至少有两次磁共振成像检查可供回顾的患者中评估了垂体后叶高信号的有无及大小的时间变化。随访磁共振成像研究显示，这些患者中8%在初次检查时无明显高信号，而随访时出现明显的垂体后叶高信号。另外25%的患者垂体后叶高信号消失。该组中19%的患者高信号大小有明显变化。我们的结果表明，垂体后叶高信号的变化应被视为一种正常的生理现象。
