Colombo N, Berry I, Kucharczyk J, Kucharczyk W, de Groot J, Larson T, Norman D, Newton T H
Department of Radiology, University of California, San Francisco.
Radiology. 1987 Nov;165(2):481-5. doi: 10.1148/radiology.165.2.3659370.
T1-weighted magnetic resonance (MR) images of the pituitary gland and sella turcica routinely demonstrate a region of high signal intensity in the neurohypophysis. High-resolution MR imaging studies of the sella turcica in 200 subjects with a normal or abnormal sella were analyzed. The hyperintensity was found in the images of about 90% of healthy subjects and patients with microadenoma, in only 43% of patients with macroadenoma, and in 12% of patients with empty sellae. The signal was absent in several patients with functional or anatomic abnormalities of the hypothalamic-hypophyseal axis. It is concluded that the high signal intensity in the posterior lobe of the pituitary gland is present in most healthy individuals and that its absence in many patients with large intrasellar masses and empty sellae is due to compression of posterior lobe tissue. Its absence in diabetes insipidus further suggests a relationship between hyperintensity and the functional status of the hypothalamic-hypophyseal axis.
垂体和蝶鞍的T1加权磁共振（MR）图像通常显示神经垂体区域有高信号强度。对200名蝶鞍正常或异常的受试者进行了蝶鞍的高分辨率MR成像研究分析。在约90%的健康受试者和微腺瘤患者的图像中发现了高信号，在大腺瘤患者中仅43%出现，在空蝶鞍患者中为12%。在一些下丘脑 - 垂体轴功能或解剖异常的患者中信号缺失。结论是，垂体后叶的高信号强度在大多数健康个体中存在，而在许多鞍内大肿块和空蝶鞍患者中其缺失是由于后叶组织受压。在尿崩症患者中其缺失进一步表明高信号与下丘脑 - 垂体轴功能状态之间的关系。
