Thorn D B, Sexton M G, Lemay A P, Sarigianis J S, Melita D D, Gustafson N J
Department of Pharmacy Services, Yale-New Haven Hospital, CT 06504.
Am J Hosp Pharm. 1989 Sep;46(9):1802-6.
Completeness of physicians' orders for cancer chemotherapy was compared before and after implementation of a preprinted form for these orders. When an oncology pharmacy service (OPS) in which pharmacy prepared all drugs for cancer chemotherapy was implemented in 1985 at an 879-bed teaching hospital, the pharmacists began educational sessions for house-staff physicians on writing orders for cancer chemotherapy. Pharmacists assessed the effectiveness of these sessions by comparing completeness of orders written before implementation of the OPS with orders during a four-week period starting two months after implementation. Orders were checked for nine components: patient's diagnosis, height, weight, and body surface area and drug regimen, dose, dosage, frequency, and route. Inclusion of the same components was assessed after implementation of a form that physicians were required to use for prescribing all antineoplastic agents. During the baseline period, orders for 143 patients were evaluated. Only two prescription components, dose and route, were present is more than 90% of the orders. Educational intervention led to some improvement in order completeness, but only dose and route appeared in at least 90% of the 87 orders evaluated. The components necessary to verify physicians' calculations for body surface area and dose--height, weight, and dosage--were absent in 29 of the orders, and a pharmacist spent 420 minutes clarifying them. After the order form was implemented, orders for 77 patients were reviewed. Compliance exceeded 90% for eight of the nine components, and 12 medication errors were prevented by the form. A pharmacist spent 70 minutes clarifying five orders.(ABSTRACT TRUNCATED AT 250 WORDS)
在实施癌症化疗医嘱预印表格前后,对医生开具的癌症化疗医嘱的完整性进行了比较。1985年,一家拥有879张床位的教学医院设立了肿瘤药学服务(OPS),由药房配制所有癌症化疗药物,药剂师开始为住院医师开展关于书写癌症化疗医嘱的培训课程。药剂师通过比较OPS实施前开具的医嘱与实施后两个月开始的四周内开具的医嘱的完整性,来评估这些培训课程的效果。医嘱检查九个项目:患者诊断、身高、体重、体表面积以及药物治疗方案、剂量、用量、频率和给药途径。在实施要求医生用于开具所有抗肿瘤药物的表格后,评估了相同项目的填写情况。在基线期,评估了143名患者的医嘱。只有两个处方项目,即剂量和给药途径,在超过90%的医嘱中出现。教育干预使医嘱完整性有所改善,但在评估的87份医嘱中,至少90%的医嘱中仅出现了剂量和给药途径。在29份医嘱中,缺少用于核实医生体表面积和剂量计算所需的项目——身高、体重和用量,一名药剂师花费420分钟进行了澄清。在实施医嘱表格后,审查了77名患者的医嘱。九个项目中的八个项目的合规率超过90%,该表格防止了12起用药错误。一名药剂师花费70分钟澄清了五份医嘱。(摘要截选至250词)