Brahmbhatt Bhaumik, Bhurwal Abhishek, Lukens Frank J, Buchanan Mauricia A, Stauffer John A, Asbun Horacio J
Division of Gastroenterology and Hepatology, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Clinical Studies Unit, Mayo Clinic, 4500 San Pablo Road, Jacksonville, FL 32224, USA.
Curr Gerontol Geriatr Res. 2016;2016:8052175. doi: 10.1155/2016/8052175. Epub 2016 Nov 27.
. Surgery is the most effective treatment for pancreatic cancer. However, present literature varies on outcomes of curative pancreatic resection in the elderly. The objective of the study was to evaluate age as an independent risk factor for 90-day mortality and complications after pancreatic resection. . Nine hundred twenty-nine consecutive patients underwent 934 pancreatic resections between March 1995 and July 2014 in a tertiary care center. Primary analyses focused on outcomes in terms of 90-day mortality and postoperative complications after pancreatic resection in these two age groups. . Even though patients aged 75 years or older had significantly more postoperative morbidities compared with the younger patient group, the age group was not associated with increased risk of 90-day mortality after pancreatic resection. . The study suggests that age alone should not preclude patients from undergoing curative pancreatic resection.
手术是胰腺癌最有效的治疗方法。然而,目前关于老年患者根治性胰腺切除术结局的文献报道存在差异。本研究的目的是评估年龄作为胰腺切除术后90天死亡率和并发症的独立危险因素。1995年3月至2014年7月期间,一家三级医疗中心的929例连续患者接受了934例胰腺切除术。主要分析集中在这两个年龄组胰腺切除术后90天死亡率和术后并发症方面的结局。尽管75岁及以上患者术后发病率明显高于年轻患者组,但该年龄组与胰腺切除术后90天死亡风险增加无关。该研究表明,仅年龄因素不应成为患者接受根治性胰腺切除术的障碍。