Ferguson Stephen A, Wang Xuewei, Meyerhoff Mark E
Department of Chemistry, University of Michigan, Ann Arbor, MI 48109-1055, USA.
Anal Methods. 2016 Aug 7;8(29):5806-5811. doi: 10.1039/C6AY01748G. Epub 2016 Jul 4.
Polymeric quaternary ammonium salts (polyquaterniums) have found increasing use in industrial and cosmetic applications in recent years. More specifically, polyquaternium-10 (PQ-10) is routinely used in cosmetic applications as a conditioner in personal care product formulations. Herein, we demonstrate the use of potentiometric polyion-sensitive polymeric membrane-based electrodes to quantify PQ-10 levels. Mixtures containing both PQ-10 and sodium lauryl sulfate (SLS) are used as model samples to illustrate this new method. SLS is often present in cosmetic samples that contain PQ-10 (e.g., shampoos, etc.) and this surfactant species interferes with the polyion sensor detection chemistry. However, it is shown here that SLS can be readily separated from the PQ-10/SLS mixture by use of an anion-exchange resin and that the PQ-10 can then be titrated with dextran sulphate (DS). This titration is monitored by potentiometric polyanion sensors to provide equivalence points that are directly proportional to PQ-10 concentrations.
近年来，聚合季铵盐（聚季铵盐）在工业和化妆品应用中的使用越来越广泛。更具体地说，聚季铵盐-10（PQ-10）在化妆品应用中经常用作个人护理产品配方中的调理剂。在此，我们展示了使用基于电位聚离子敏感聚合物膜的电极来定量PQ-10水平。含有PQ-10和月桂基硫酸钠（SLS）的混合物用作模型样品来说明这种新方法。SLS经常存在于含有PQ-10的化妆品样品中（例如洗发水等），并且这种表面活性剂会干扰聚离子传感器的检测化学。然而，此处表明，通过使用阴离子交换树脂可以很容易地将SLS与PQ-10/SLS混合物分离，然后可以用硫酸葡聚糖（DS）滴定PQ-10。通过电位聚阴离子传感器监测这种滴定，以提供与PQ-10浓度成正比的等当点。
