Xu Chong, Li Wenxi, Lin Lin, Zhang Dexiang, Lei Jinyu, Pan Danyang, Liang Shuangcheng, Chen Yiti, Wan Yuepeng, He Jingyu
Research Center of New Material, Guangzhou Uniasia Cosmetics Technology Co., Ltd, Guangzhou, 510663, China.
Guangdong Jiangmen Chinese Medicine College, Jiangmen, 529000, China.
BMC Microbiol. 2025 Aug 11;25(1):497. doi: 10.1186/s12866-025-04260-5.
Shampoo, a crucial personal hygiene product, holds significant economic importance. Given the complex interactions of the scalp microbiome and its impact on scalp and hair health, understanding how shampoo affects this ecosystem is vital. Results showed that 28-day shampoo use significantly increased scalp moisture content (P = 0.04) without affecting sebum secretion P = 0.23. Regarding the bacterial community, while alpha diversity indices showed no significant changes, the relative abundance of Proteobacteria was decreased significantly, and the relative abundance of Actinobacteriota was increased significantly; the relative abundance of Cutibacterium genus was increased significantly, from 11.58 to 28.66%, more abundant than Staphylococcus genus (from 16.55 to 18.37%). For the fungal community, the Chao 1 index decreased significantly, and the relative abundances of several phyla and genera changed, but retained the core microbiome (Malassezia). Canonical correspondence analysis revealed that the microbial communities shifted from an oily environment to a more moisturized environment. Network analysis showed different co-occurrence relationships between core taxa and physicochemical factors for bacteria and fungi. Functional prediction via PICRUSt2 and FUNGuild indicated that the shampoo altered metabolic pathways of bacteria and the trophic modes of fungi. In conclusion, the study described the complex community dynamics of scalp microorganisms before and after 28-day shampoo use. The results will help improve the interactions among shampoo, scalp microbiota, and scalp physiology, offering valuable insights for the development of scalp and hair care products and strategies.
洗发水作为一种关键的个人卫生用品，具有重要的经济意义。鉴于头皮微生物群的复杂相互作用及其对头皮和头发健康的影响，了解洗发水如何影响这个生态系统至关重要。结果显示，使用28天洗发水后，头皮水分含量显著增加（P = 0.04），而皮脂分泌不受影响（P = 0.23）。关于细菌群落，虽然α多样性指数没有显著变化，但变形菌门的相对丰度显著降低，放线菌门的相对丰度显著增加；棒状杆菌属的相对丰度显著增加，从11.58%增至28.66%，比葡萄球菌属（从16.55%增至18.37%）更为丰富。对于真菌群落，Chao 1指数显著下降，几个门和属的相对丰度发生了变化，但核心微生物群（马拉色菌）依然存在。典范对应分析表明，微生物群落从油性环境转变为更湿润的环境。网络分析显示，细菌和真菌的核心分类群与理化因素之间存在不同的共现关系。通过PICRUSt2和FUNGuild进行的功能预测表明，洗发水改变了细菌的代谢途径和真菌的营养模式。总之，该研究描述了使用28天洗发水前后头皮微生物的复杂群落动态。这些结果将有助于改善洗发水、头皮微生物群和头皮生理之间的相互作用，为头皮和头发护理产品及策略的开发提供有价值的见解。
