来自驱虫斑鸠菊种子的两种新化合物。
Two new compounds from the seeds of Vernonia anthelmintica.
作者信息
Maimaiti Zulipiya, Turak Ablajan, Aisa Haji Akber
机构信息
a State Key Laboratory Basis of Xinjiang Indigenous Medicinal Plants Resource Utilization , Xinjiang Technical Institute of Physics and Chemistry, Chinese Academy of Sciences , Urumqi 830011 , China.
b University of the Chinese Academy of Sciences , Beijing 100039 , China.
出版信息
J Asian Nat Prod Res. 2017 Sep;19(9):862-868. doi: 10.1080/10286020.2016.1269760. Epub 2016 Dec 25.
Two new compounds, named benzoyl-vernovan (1) and 2-(4'-hydroxyphenyl)-6-methyl-4H-pyran-4-one (2), together with one biflavonoid (3), one aurone (4) and six flavonoids were isolated from the seeds of Vernonia anthelmintica. Their structures were elucidated by extensive spectroscopic analyses and comparison with published data, and their influence on melanin content in B16 melanoma cells were tested. 5 and 9 increased melanin content by 2.2% and 30.9% higher than positive control 8-methoxypsoralen.
从驱虫斑鸠菊种子中分离出两种新化合物，分别命名为苯甲酰-斑鸠菊烷（1）和2-（4'-羟基苯基）-6-甲基-4H-吡喃-4-酮（2），以及一种双黄酮（3）、一种橙酮（4）和六种黄酮类化合物。通过广泛的光谱分析并与已发表的数据进行比较来阐明它们的结构，并测试了它们对B16黑色素瘤细胞中黑色素含量的影响。5和9使黑色素含量比阳性对照8-甲氧基补骨脂素分别增加了2.2%和30.9%。
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