Vasilev D, Katsarova M, Dikov I
Akush Ginekol (Sofiia). 1989;28(3):63-6.
The authors carried out studies on 80 women, using Trisistone, a preparation of Germed, Jenapharm, DDR, in the course of 250 cycles, taking into consideration the advantages of triphasic contraceptive preparations as well as the fact that till this moment there were not applied in our country. A good contraceptive efficiency was established. No case with conception was recorded. The side effects were mild and and their frequency varies between 2.4 and 9.7% Irregular bleedings were the only disadvantage of Trisistone, which caused refusal for its usage. It is proposed that Trisistone should be used as an initial contraceptive preparation like the preparations with "mini" doses. In cases with good tolerance women should continue to use it, but they should take another contraceptive preparation, when bleeding occurs.
作者对80名女性进行了研究，在250个周期中使用了民主德国耶拿制药厂生产的三烯高诺酮制剂“Trisistone”，同时考虑到三相避孕制剂的优点以及当时我国尚未应用这一情况。研究确立了良好的避孕效果。未记录到怀孕案例。副作用轻微，其发生率在2.4%至9.7%之间。不规则出血是三烯高诺酮唯一的缺点，这导致一些女性拒绝使用它。建议将三烯高诺酮像“小剂量”制剂一样用作初始避孕制剂。对于耐受性良好的女性，应继续使用它，但在出现出血情况时应更换为其他避孕制剂。
