Sciotto A, Russo-Mancuso G, Zinna C M, Comisi F F, Sciannaca R M, Schiliro G
Department of Pediatrics, University of Catania, Italy.
Ann Allergy. 1989 Oct;63(4):343-6.
We examined lymphocyte subsets in peripheral blood from children with visceral leishmaniasis both in the active stage of the disease and after recovery. At diagnosis, CD2+ and CD4+ cells showed a significant decrease while CD8+ cells were significantly increased when compared with controls; CD4/CD8 ratio was inverted. All of these alterations returned to normal values 3 months after recovery.
我们检测了内脏利什曼病患儿在疾病活动期及康复后的外周血淋巴细胞亚群。诊断时，与对照组相比，CD2⁺和CD4⁺细胞显著减少，而CD8⁺细胞显著增加；CD4/CD8比值倒置。康复3个月后，所有这些改变均恢复至正常水平。
