Swecker W S, Eversole D E, Thatcher C D, Blodgett D J, Schurig G G, Meldrum J B
Department of Large Animal Clinical Sciences, Virginia-Maryland Regional College of Veterinary Medicine, Blacksburg 24061.
Am J Vet Res. 1989 Oct;50(10):1760-3.
Influence of supplemental Se on humoral immune response was measured in 60 weaned beef calves with marginal blood Se status. Calves were fed a Se-deficient diet consisting of corn silage, corn grain, and soybean meal. Blood Se concentrations, primary and secondary humoral immune responses to hen egg lysozyme inoculation, and weight gain were determined in a 70-day trial. Calves fed 20 mg of Se/kg of mineral mixture ad libitum had lower antibody responses (P less than 0.02), compared with calves fed 20 mg of Se/kg of mineral mixture and given 0.1 mg of Se and 0.22 IU of vitamin E/kg of body weight, IM, or with calves fed 80, 120, 160, or 200 mg of Se/kg of mineral mixture. Calves fed 80, 120, 160, or 200 mg of Se/kg of mineral mixture had higher (P less than 0.001) blood Se concentrations on day 70, compared with calves fed 20 mg of Se/kg of mineral mixture and given 0.1 mg of Se and 0.22 IU of vitamin E/kg of body weight, IM. Selenium supplementation had no effect on weight gain.
在60头血液硒水平处于临界状态的断奶肉牛犊中，测定了补充硒对体液免疫反应的影响。犊牛饲喂由玉米青贮、玉米籽粒和豆粕组成的缺硒日粮。在一项为期70天的试验中，测定了血液硒浓度、对鸡蛋溶菌酶接种的初次和二次体液免疫反应以及体重增加情况。与饲喂20mg硒/kg矿物质混合物并肌肉注射0.1mg硒和0.22IU维生素E/kg体重的犊牛相比，随意采食20mg硒/kg矿物质混合物的犊牛抗体反应较低（P<0.02）；与饲喂20mg硒/kg矿物质混合物并肌肉注射0.1mg硒和0.22IU维生素E/kg体重的犊牛相比，饲喂80、120、160或200mg硒/kg矿物质混合物的犊牛在第70天血液硒浓度较高（P<0.001）。补充硒对体重增加没有影响。
