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[对感染人类免疫缺陷病毒的母亲所生新生儿的前瞻性研究]

[Prospective study of newborn infants born to mothers infected with human immunodeficiency virus].

作者信息

Echeverría Lecuona J, Oliveros Vela M, Cilla Eguiluz G, Cuadrado del Barrio E, Albisu Andrade Y

机构信息

Departamento de Pediatría, Hospital Materno-Infantil, Nuestra Señora de Aránzazu, San Sebastián.

出版信息

An Esp Pediatr. 1989 Jun;30(6):429-31.

PMID:2802391
Abstract

Perinatal transmission of Human immunodeficiency virus (HIV) from mother to child is at the present time the most important cause of AIDS in children. Since August 1985 we have observed 24 babies with anti-HIV antibodies born to HIV-infected mothers. Their present status is: 6 have symptomatic infection, 6 undetermined infection, 10 had became seronegative and 2 were lost for follow-up. Our results suggest that the risk of infection for the baby is high and the onset of symptoms relatively early. Follow-up studies in babies born to HIV-infected mothers are needed in order to classify the true risk of infection in them and the natural history of the disease.

摘要

目前,人类免疫缺陷病毒(HIV)的围产期母婴传播是儿童艾滋病的最重要病因。自1985年8月以来,我们观察了24名感染HIV的母亲所生的有抗HIV抗体的婴儿。他们目前的状况是:6名有症状感染,6名感染情况未确定,10名已转为血清阴性,2名失访。我们的结果表明,婴儿的感染风险很高,且症状出现相对较早。为了明确感染HIV的母亲所生婴儿的真正感染风险及该疾病的自然史,需要对这些婴儿进行随访研究。

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