Aguayo Maldonado J, Salmerón Escobar F J, Bonal Pitz P P, Aguayo Maldonado A L, Loscertales Abril M, Gómez Vida J M, Ruiz Extremera A
Licenciado en Ciencias Físicas, Hospital Universitario de Granada, Departamento de Pediatría.
An Esp Pediatr. 1989 Jun;30(6):435-42.
A study was made of polynuclear leucocyte function: chemotaxis, NBT reduction and the influence of total plasma on chemotaxis, was investigated in a large group of asthmatic paediatric patients, both during and between asthmatic attacks. It has been proved that polynuclear function is different in the two types of asthma. During the asthmatic's crisis and in the intrinsic patients in intercrisis periods, there is a polynuclear neutrophil hyperreaction when the chemotaxis and the NBT reduction are raised. An inhibited chemotactic activity in the plasma of these patients is noted. This activity doesn't produce irreversible effects on the cells; it acts as a regulating mechanism on the chemotactic factors found in plasmatic fractions.
研究了趋化性、NBT还原以及全血浆对趋化性的影响。已证明两种类型哮喘的多核白细胞功能存在差异。在哮喘发作期以及内在型患者发作间隙期，当趋化性和NBT还原增加时，存在多核中性粒细胞高反应性。注意到这些患者血浆中的趋化活性受到抑制。这种活性不会对细胞产生不可逆影响；它对血浆成分中发现的趋化因子起调节机制的作用。
