Prowse K, Allen M B, Bradbury S P
Ann Occup Hyg. 1989;33(3):375-85. doi: 10.1093/annhyg/33.3.375.
Respiratory symptoms, smoking habit, lung function and radiological category of silicosis were assessed in 276 present and former pottery workers who were receiving industrial disablement benefit for silicosis. There were 140 females and 136 males. The proportion with conglomerate disease (massive fibrosis) was similar in both sexes. The FEV1 declined with increasing X-ray category of silicosis irrespective of smoking habit and was most marked in subjects with symptomatic chronic bronchitis. In females who had never smoked the average decline of FEV1 in those with simple silicosis was 18 ml year-1 and for those with conglomerate disease 38 ml year-1. Symptomatic chronic bronchitis was common and only partly related to smoking, occurring in 69% of 101 nonsmoking female silicotic patients. No significant changes were observed in vital capacity, lung volume or transfer factor for carbon monoxide.
对276名目前和曾经从事制陶工作且因矽肺领取工业伤残抚恤金的工人，评估了他们的呼吸系统症状、吸烟习惯、肺功能以及矽肺的放射学分类。其中女性140人，男性136人。两性别中合并症（块状纤维化）的比例相似。第一秒用力呼气容积（FEV1）随矽肺X线分类的增加而下降，与吸烟习惯无关，在有症状的慢性支气管炎患者中最为明显。在从不吸烟的女性中，单纯矽肺患者FEV1的平均年下降量为18毫升，合并症患者为38毫升/年。有症状的慢性支气管炎很常见，且仅部分与吸烟有关，在101名不吸烟的女性矽肺患者中发病率为69%。肺活量、肺容积或一氧化碳转运因子未观察到显著变化。
