Eskelinen M, Collán Y, Puittinen J, Pajarinen P, Alhava E
Department of Surgery, Kuopio University Central Hospital, Finland.
Ann Chir Gynaecol. 1989;78(2):149-52.
Three cases of malignant lymphoma of the breast are described, seen over a 14 year period in the district of Kuopio University Central Hospital. The neoplasms were either of high or intermediate grade of malignancy: one immunoblastic, one Burkitt-type, and one centroblastic-centrocytic malignant lymphoma. The patient with centroblastic-centrocytic malignant lymphoma had advanced disease with pulmonary and adenoidal involvement and died 15 months after the detection of the breast tumor. The two other neoplasms were confined to the breast with no evidence of further dissemination. The patient with immunoblastic malignant lymphoma developed intestinal lymphoma 3 years later which was treated with surgery and cytostatic therapy. The patient has since been in remission for a period of 10.5 years. The patient with Burkitt-type malignant lymphoma was subjected to surgical resection which was followed by cytostatic treatment. The patient has remained in good health during the 20-month follow-up. The correct diagnosis is especially important in breast lymphoma because without it the appropriate treatment cannot be applied.
本文描述了三例乳腺恶性淋巴瘤病例，这些病例是在库奥皮奥大学中心医院所在地区14年期间发现的。肿瘤的恶性程度为高或中度：一例为免疫母细胞型，一例为伯基特型，一例为中心母细胞-中心细胞型恶性淋巴瘤。中心母细胞-中心细胞型恶性淋巴瘤患者的病情已进展至肺部和腺样体受累，在乳腺肿瘤被发现15个月后死亡。另外两例肿瘤局限于乳腺，无进一步扩散的迹象。免疫母细胞型恶性淋巴瘤患者3年后发生肠道淋巴瘤，接受了手术和细胞抑制治疗。此后，该患者已缓解10.5年。伯基特型恶性淋巴瘤患者接受了手术切除，随后进行了细胞抑制治疗。在20个月的随访期间，该患者一直保持健康。在乳腺淋巴瘤中，正确的诊断尤为重要，因为没有正确诊断就无法进行适当的治疗。
