Kim Na Hee, Yun Sook Jung, Lee Jee-Bum
Department of Dermatology, Chonnam National University Medical School, Gwangju, Korea.
J Dermatol. 2017 Jun;44(6):710-712. doi: 10.1111/1346-8138.13714. Epub 2016 Dec 27.
Rhinophyma results from hyperplasia of the sebaceous glands and connective tissue. Clinical features in Asian rhinophyma patients are largely underreported. In this study, we aimed to evaluate the clinical features of rhinophyma in Korean patients. We reviewed clinical photos and medical records of 39 Korean patients diagnosed with rhinophyma and assessed the severity and clinical course by using the classical National Rosacea Society index. The male : female ratio was 6.8:1, and over 90% of the patients were older than 40 years. The mild-grade rhinophyma was the most dominant (46.1%), followed by the moderate (41.0%) and severe (12.8%) grades. Disease progression to severe grade occurred over an average of 8.2 years. Furthermore, 70% of all cases revealed lesion distribution limited to the nose. As disease severity progressed to higher grades, the extent of nasal involvement increased (Pearson correlation coefficient, 0.685). Rhinophyma is a slowly progressing disease showing male predominance unrelated to specific trigger factors. In many cases, this disease often exclusively affects the nose in Asian patients.
酒渣鼻是由皮脂腺和结缔组织增生引起的。亚洲酒渣鼻患者的临床特征在很大程度上鲜有报道。在本研究中，我们旨在评估韩国患者酒渣鼻的临床特征。我们回顾了39例诊断为酒渣鼻的韩国患者的临床照片和病历，并使用经典的国家酒渣鼻协会指数评估严重程度和临床病程。男女比例为6.8:1，超过90%的患者年龄超过40岁。轻度酒渣鼻最为常见（46.1%），其次是中度（41.0%）和重度（12.8%）。疾病进展到重度平均需要8.2年。此外，所有病例中有70%显示病变仅局限于鼻子。随着疾病严重程度进展到更高等级，鼻腔受累范围增加（Pearson相关系数，0.685）。酒渣鼻是一种进展缓慢的疾病，男性居多，与特定触发因素无关。在许多情况下，这种疾病在亚洲患者中往往仅累及鼻子。
