Goździewicz B, Strugała M, Talarska D, Stanisławska J, Bączyk G
Greater Poland Cancer Centre, Poznań, Poland.
Department of Preventive Medicine, Karol Marcinkowski University of Medical Sciences, Poznań, Poland.
Eur J Cancer Care (Engl). 2017 May;26(3). doi: 10.1111/ecc.12616. Epub 2016 Dec 27.
Cancer of the colon is one of the most common malignant tumours in both genders. Thanks to the development of diagnostic techniques, lesions can be detected early fostering full patient's recovery. The aim of this study was to investigate factors affecting quality of life of patients with colorectal cancer (CRC) during chemotherapy. The research tool was a questionnaire of our own design that allows collecting demographic and clinical data and Functional Assessment of Cancer Therapy Scale-Colorectal (FACT-C). The study included 90 patients. The analysis confirmed the difference between Social-Family Well-Being (SWB) and Emotional Well-Being (EWB) and in the overall assessment of quality of life and age. Taking into account the presence of stoma, a statistically significant difference was found only in the Colorectal Cancer Subscale (CCS p = .01321). Regarding the number of cycles of chemotherapy, a statistically significant difference was shown in the overall evaluation (p = .0459) and the SWB (p = .0463) area. In patients with CRC in the general assessment of quality of life, which is at a medium level, non-modifiable factors like age and gender play a minor role when compared with the group of variables related to the process and treatment of the disease.
结肠癌是男女中最常见的恶性肿瘤之一。由于诊断技术的发展，病变能够早期被检测出来，从而促进患者的完全康复。本研究的目的是调查影响结直肠癌（CRC）患者化疗期间生活质量的因素。研究工具是我们自己设计的一份问卷，该问卷能够收集人口统计学和临床数据以及癌症治疗功能评估量表 - 结直肠癌（FACT - C）。该研究纳入了90名患者。分析证实了社会 - 家庭幸福感（SWB）与情感幸福感（EWB）之间以及生活质量总体评估与年龄之间存在差异。考虑到造口的存在，仅在结直肠癌子量表中发现了统计学上的显著差异（CCS p = 0.01321）。关于化疗周期数，在总体评估（p = 0.0459）和SWB（p = 0.0463）方面显示出统计学上的显著差异。在结直肠癌患者生活质量的总体评估中处于中等水平，与疾病过程和治疗相关的变量组相比，年龄和性别等不可改变的因素作用较小。
