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评价在泰国接受门诊家庭化疗的结直肠癌患者的不良事件和与健康相关的生活质量。

Evaluation of adverse events and health-related quality of life in patients with colorectal cancer receiving ambulatory home-based chemotherapy in Thailand.

机构信息

Department of Nursing, Faculty of Medicine Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

Department of Nursing, Somdech Phra Debaratana Medical Center Ramathibodi Hospital, Mahidol University, Bangkok, Thailand.

出版信息

Nurs Open. 2021 Nov;8(6):3036-3044. doi: 10.1002/nop2.1016. Epub 2021 Aug 12.

DOI:10.1002/nop2.1016
PMID:34382364
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8510724/
Abstract

AIMS: To compare adverse events and health-related quality of life in ambulatory home-based chemotherapy with those in inpatient. DESIGN: Prospective non-randomized observational study. METHODS: Participants were divided into two groups according to patients' preference receiving chemotherapy. RESULTS: Sixty-four participants were enrolled in the inpatient, and 111 were in an ambulatory home-based chemotherapy. The frequency of anaemia, neutropenia and thrombocytopenia was significantly higher in inpatient group than in ambulatory home-based chemotherapy group (p < .001, <.001 and .002, respectively). Nausea, mucositis, and fatigue were more common in ambulatory home-based chemotherapy group than in inpatient group (p < .001, .022, and .005, respectively). Patients in the ambulatory home-based chemotherapy group showed higher social well-being (SWB) scores than inpatient group (coefficient 1.92, 95% confidence interval [CI] 0.65 to 3.19, p .003).

摘要

目的：比较门诊家庭化疗与住院化疗的不良事件和健康相关生活质量。 设计：前瞻性非随机观察性研究。 方法：根据患者的偏好，将参与者分为两组接受化疗。 结果：64 名参与者被纳入住院组，111 名参与者被纳入门诊家庭化疗组。住院组贫血、中性粒细胞减少和血小板减少的发生率明显高于门诊家庭化疗组（p<0.001、<.001 和<.002，分别）。恶心、黏膜炎和疲劳在门诊家庭化疗组比住院组更常见（p<0.001、<.022 和<.005，分别）。门诊家庭化疗组的患者比住院组的患者具有更高的社会福利（SWB）评分（系数 1.92，95%置信区间 [CI] 0.65 至 3.19，p<.003）。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fd0/8510724/6b139416ac3b/NOP2-8-3036-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fd0/8510724/75727de16c84/NOP2-8-3036-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fd0/8510724/6b139416ac3b/NOP2-8-3036-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fd0/8510724/75727de16c84/NOP2-8-3036-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2fd0/8510724/6b139416ac3b/NOP2-8-3036-g002.jpg

相似文献

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Evaluation of adverse events and health-related quality of life in patients with colorectal cancer receiving ambulatory home-based chemotherapy in Thailand.

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[1]
Hospital at home for oncologic patients: SEOM-SEHAD consensus on clinical practice.

Clin Transl Oncol. 2025-4-23

[2]
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Cochrane Database Syst Rev. 2025-4-22

[3]
Efficacy and Safety of Anti-EGFR Therapy Rechallenge in Metastatic Colorectal Cancer: A Systematic Review and Meta-Analysis.

J Gastrointest Cancer. 2024-10-22

[4]
Nurse-Led Care at Home Visit Versus Standard Care in Patients with Mild Acute Pancreatitis: A Retrospective Analysis.

Dig Dis Sci. 2024-8

[5]
"It's a part of the patient": The experiences of patients with cancer undergoing home-based chemotherapy from patients' and nurses' perspectives.

Asia Pac J Oncol Nurs. 2022-4-22

本文引用的文献

[1]
Home-based chemotherapy for stage III colon cancer patients in Thailand: Cost-utility and budget impact analyses.

Cancer Med. 2021-2

[2]
Epidemiology of colorectal cancer: incidence, mortality, survival, and risk factors.

Prz Gastroenterol. 2019

[3]
An observational pilot study to evaluate the feasibility and quality of oncological home-hospitalization.

Eur J Oncol Nurs. 2019-3-23

[4]
Reducing Hospitalizations: Institution of Outpatient Infusional EPOCH-Based Chemotherapy at a Safety Net Hospital.

J Oncol Pract. 2019-6-17

[5]
Evaluation of Quality of Life and Health Care Needs in Cancer Patients Receiving Chemotherapy.

J Cancer Educ. 2020-8

[6]
Organization, quality and cost of oncological home-hospitalization: A systematic review.

Crit Rev Oncol Hematol. 2018-4-10

[7]
Quality of life in cancer patients-a comparison of inpatient, outpatient, and rehabilitation settings.

Support Care Cancer. 2018-4-26

[8]
The Hospital at Home program: no place like home.

Curr Oncol. 2017-2

[9]
Functioning of people with colorectal cancer during chemotherapy. Demographic and clinical determinants of quality of life of patients with colorectal cancer receiving chemotherapy. Pilot study.

Eur J Cancer Care (Engl). 2017-5

[10]
Home administration of bortezomib in multiple myeloma is cost-effective and is preferred by patients compared with hospital administration: results of a prospective single-center study.

Ann Oncol. 2015-11-16

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