Orton Elizabeth, Whitehead Jessica, Mhizha-Murira Jacqueline, Clarkson Mandy, Watson Michael C, Mulvaney Caroline A, Staniforth Joy Ul, Bhuchar Munish, Kendrick Denise
Division of Primary Care, University of Nottingham, Room 1313, Tower Building, University Park, Nottingham, UK, NG7 2RD.
School of Health Sciences, The University of Nottingham, B Floor, South Block Link, Queens Medical Centre, Nottingham, UK, NG7 2HA.
Cochrane Database Syst Rev. 2016 Dec 27;12(12):CD010246. doi: 10.1002/14651858.CD010246.pub2.
Unintentional injuries are the leading cause of death in children aged four to 18 years and are a major cause of ill health. The school setting offers the opportunity to deliver preventive interventions to a large number of children and has been used to address a range of public health problems. However, the effectiveness of the school setting for the prevention of different injury mechanisms in school-aged children is not well understood.
To assess the effects of school-based educational programmes for the prevention of injuries in children and evaluate their impact on improving children's safety skills, behaviour and practices, and knowledge, and assess their cost-effectiveness.
We ran the most recent searches up to 16 September 2016 for the following electronic databases: Cochrane Injuries Group Specialised Register; Cochrane Central Register of Controlled Trials; Ovid MEDLINE(R), Ovid MEDLINE(R) In-Process & Other Non-Indexed Citations; Ovid MEDLINE(R) Daily and Ovid OLDMEDLINE(R); Embase and Embase Classic (Ovid); ISI Web of Science: Science Citation Index Expanded; ISI Web of Science Conference Proceedings Citation Index-Science; ISI Web of Science: Social Sciences Citation Index; ISI Web of Science: Conference Proceedings Citation Index - Social Sciences & Humanities; and the 14 October 2016 for the following electronic databases: Health Economics Evaluations Database (HEED); Health Technology Assessment Database (HTA); CINAHL Plus (EBSCO); ZETOC; LILACS; PsycINFO; ERIC; Dissertation Abstracts Online; IBSS; BEI; ASSIA; CSA Sociological Abstracts; Injury Prevention Web; SafetyLit; EconLit (US); PAIS; UK Clinical Research Network Study Portfolio; Open Grey; Index to Theses in the UK and Ireland; Bibliomap and TRoPHI.
We included randomised controlled trials (RCTs), non-randomised controlled trials (non-RCTs), and controlled before-and-after (CBA) studies that evaluated school-based educational programmes aimed at preventing a range of injury mechanisms. The primary outcome was self-reported or medically attended unintentional (or unspecified intent) injuries and secondary outcomes were observed safety skills, observed behaviour, self-reported behaviour and safety practices, safety knowledge, and health economic outcomes. The control groups received no intervention, a delayed injury-prevention intervention or alternative school-based curricular activities. We included studies that aimed interventions at primary or secondary prevention of injuries from more than one injury mechanism and were delivered, in part or in full, in schools catering for children aged four to 18 years.
We used standard methodological procedures expected by Cochrane. Two review authors identified relevant trials from title and abstracts of studies identified in searches and two review authors extracted data from the included studies and assessed risk of bias. We grouped different types of interventions according to the outcome assessed and the injury mechanism targeted. Where data permitted, we performed random-effects meta-analyses to provide a summary of results across studies.
The review included 27 studies reported in 30 articles. The studies had 73,557 participants with 12 studies from the US; four from China; two from each of Australia, Canada, the Netherlands and the UK; and one from each of Israel, Greece and Brazil. Thirteen studies were RCTs, six were non-RCTs and eight were CBAs. Of the included studies, 18 provided some element of the intervention in children aged four to 11 years, 17 studies included children aged 11 to 14 years and nine studies included children aged 14 to 18 years.The overall quality of the results was poor, with the all studies assessed as being at high or unclear risks of bias across multiple domains, and varied interventions and data collection methods employed. Interventions comprised information-giving, peer education or were multi-component.Seven studies reported the primary outcome of injury occurrence and only three of these were similar enough to combine in a meta-analysis, with a pooled incidence rate ratio of 0.73 (95% confidence interval (CI) 0.49 to 1.08; 2073 children) and substantial statistical heterogeneity (I = 63%). However, this body of evidence was low certainty, due to concerns over this heterogeneity (inconsistency) and imprecision. This heterogeneity may be explained by the non-RCT study design of one of the studies, as a sensitivity analysis with this study removed found stronger evidence of an effect and no heterogeneity (I = 0%).Two studies report an improvement in safety skills in the intervention group. Likewise, the four studies measuring observed safety behaviour reported an improvement in the intervention group relative to the control. Thirteen out of 19 studies describing self-reported behaviour and safety practices showed improvements, and of the 21 studies assessing changes in safety knowledge, 19 reported an improvement in at least one question domain in the intervention compared to the control group. However, we were unable to pool data for our secondary outcomes, so our conclusions were limited, as they were drawn from highly diverse single studies and the body of evidence was low (safety skills) or very low (behaviour, safety knowledge) certainty. Only one study reported intervention costs but did not undertake a full economic evaluation (very low certainty evidence).
AUTHORS' CONCLUSIONS: There is insufficient evidence to determine whether school-based educational programmes can prevent unintentional injuries. More high-quality studies are needed to evaluate the impact of educational programmes on injury occurrence. There is some weak evidence that such programmes improve safety skills, behaviour/practices and knowledge, although the evidence was of low or very low quality certainty. We found insufficient economic studies to assess cost-effectiveness.
意外伤害是4至18岁儿童的主要死因,也是健康不佳的主要原因。学校环境为向大量儿童提供预防干预措施提供了机会,并且已被用于解决一系列公共卫生问题。然而,学校环境对预防学龄儿童不同伤害机制的有效性尚未得到充分理解。
评估以学校为基础的教育项目对预防儿童伤害的效果,并评估其对提高儿童安全技能、行为和实践以及知识的影响,并评估其成本效益。
我们截至2016年9月16日对以下电子数据库进行了最新检索:Cochrane伤害小组专业注册库;Cochrane对照试验中心注册库;Ovid MEDLINE(R)、Ovid MEDLINE(R)在研及其他未索引引文;Ovid MEDLINE(R)日报和Ovid OLDMEDLINE(R);Embase和Embase经典版(Ovid);ISI科学网:科学引文索引扩展版;ISI科学网会议论文引文索引 - 科学版;ISI科学网:社会科学引文索引;ISI科学网:会议论文引文索引 - 社会科学与人文版;以及截至2016年10月14日对以下电子数据库进行检索:卫生经济学评估数据库(HEED);卫生技术评估数据库(HTA);CINAHL Plus(EBSCO);ZETOC;LILACS;PsycINFO;ERIC;在线学位论文摘要;IBSS;BEI;ASSIA;CSA社会学文摘;伤害预防网;SafetyLit;美国经济文献数据库(EconLit);PAIS;英国临床研究网络研究组合;Open Grey;英国和爱尔兰论文索引;Bibliomap和TRoPHI。
我们纳入了评估旨在预防一系列伤害机制的以学校为基础的教育项目的随机对照试验(RCT)、非随机对照试验(非RCT)和前后对照(CBA)研究。主要结局是自我报告或就医的意外伤害(或未明确意图的伤害),次要结局是观察到的安全技能、观察到的行为、自我报告的行为和安全实践、安全知识以及卫生经济结局。对照组未接受干预、接受延迟的伤害预防干预或替代性的校本课程活动。我们纳入了旨在对多种伤害机制进行伤害一级或二级预防干预的研究,这些干预部分或全部在为4至18岁儿童服务的学校中实施。
我们采用了Cochrane期望的标准方法程序。两位综述作者从检索到的研究标题和摘要中识别相关试验,两位综述作者从纳入研究中提取数据并评估偏倚风险。我们根据评估的结局和针对的伤害机制对不同类型的干预进行分组。在数据允许的情况下,我们进行随机效应荟萃分析以汇总各项研究的结果。
该综述纳入了30篇文章中报告的27项研究。这些研究共有73557名参与者,其中12项研究来自美国;4项来自中国;澳大利亚、加拿大、荷兰和英国各有2项;以色列、希腊和巴西各有1项。13项研究为RCT,6项为非RCT,8项为CBA。在纳入的研究中,18项对4至11岁儿童提供了某种形式的干预,17项研究纳入了11至14岁儿童,9项研究纳入了14至18岁儿童。结果的总体质量较差,所有研究在多个领域被评估为具有高或不明确的偏倚风险,并且采用了不同的干预措施和数据收集方法。干预措施包括提供信息、同伴教育或为多成分干预。7项研究报告了伤害发生的主要结局,其中只有3项足够相似,可以合并进行荟萃分析,合并发生率比为0.73(95%置信区间(CI)0.49至1.08;2073名儿童),且存在显著的统计学异质性(I² = 63%)。然而,由于对这种异质性(不一致性)和不精确性的担忧,这组证据的确定性较低。这种异质性可能是由于其中一项研究的非RCT研究设计所致,因为剔除该研究后的敏感性分析发现了更强的效应证据且无异质性(I² = 0%)。两项研究报告干预组的安全技能有所改善。同样,4项测量观察到的安全行为的研究报告干预组相对于对照组有所改善。1描述自我报告行为和安全实践的19项研究中有13项显示有所改善,在评估安全知识变化的21项研究中,19项报告干预组与对照组相比至少在一个问题领域有所改善。然而,我们无法汇总次要结局的数据,因此我们的结论有限,因为它们是从高度多样化的单一研究中得出的,且证据的确定性较低(安全技能)或非常低(行为、安全知识)。只有一项研究报告了干预成本,但未进行全面的经济评估(证据确定性非常低)。
没有足够的证据来确定以学校为基础的教育项目是否能预防意外伤害。需要更多高质量的研究来评估教育项目对伤害发生的影响。有一些微弱的证据表明此类项目可改善安全技能、行为/实践和知识,尽管证据的质量确定性低或非常低。我们发现评估成本效益的经济研究不足。