Department of Immunology - Allergology - Rheumatology, Faculty of Medicine and Health Science, University of Antwerp and Antwerp University Hospital, Wilrijk, Belgium.
Immunology Department, Centre de Diagnòstic Biomèdic (CDB), Hospital Clínic, Universitat de Barcelona and Institut d'Investigacions Biomèdiques August Pi i Sunyer (IDIBAPS), Barcelona, Spain.
Allergy. 2017 Jun;72(6):842-848. doi: 10.1111/all.13115. Epub 2017 Jan 19.
IgE-mediated shellfish allergy constitutes an important cause of food-related adverse reactions. Shellfish are classified into mollusks and crustaceans, the latter belonging to the class of arthropoda. Among crustaceans, shrimps are the most predominant cause of allergic reactions and thus more extensively studied. Several major and minor allergens have been identified and cloned. Among them, invertebrate tropomyosin, arginine kinase, myosin light chain, sarcoplasmic calcium-binding protein, and hemocyanin are the most relevant. This review summarizes our current knowledge about these allergens.
IgE 介导的贝类过敏是食物相关不良反应的重要原因。贝类分为软体动物和甲壳类动物，后者属于节肢动物门。在甲壳类动物中，虾是引起过敏反应的最主要原因，因此研究得更为广泛。已经鉴定和克隆了几种主要和次要过敏原。其中，无脊椎动物原肌球蛋白、精氨酸激酶、肌球蛋白轻链、肌浆钙结合蛋白和血蓝蛋白最为相关。本文综述了这些过敏原的最新知识。
