Buck I, Lindner C, Böge K, Kitschke H J
Universitätsfrauenklinik Hamburg.
Arch Gynecol Obstet. 1989;245(1-4):674-7. doi: 10.1007/BF02417494.
Tumor marker serum levels of 580 patients in different stages of breast cancer were examined in a retrospective analysis. Patients with nonmetastatic breast cancer showed a preoperatively elevated CA 15-3 in 16% and an elevation of CEA in 12%. In case of local recurrence in 24% CA 15-3- and in 9% CEA-levels were positive. The sensitivity of both markers increased in stage of distant metastasis (58%/48%). CA 15-3 was significantly more sensitive than CEA in case of visceral metastatic spread (56%/34%).
