Muslihah Nurul, Khomsan Ali, Briawan Dodik, Riyadi Hadi
Department of Nutrition Science, Faculty of Medicine, University of Brawijaya, Indonesia. Email:
Department of Community Nutrition, Faculty of Human Ecology, Bogor Agricultural University, Indonesia.
Asia Pac J Clin Nutr. 2016 Dec;25(Suppl 1):S36-S42. doi: 10.6133/apjcn.122016.s9.
Stunting during childhood is a common public health problem in Indonesia. Complementary food supplementation with a small quantity of lipid-based nutrient supplements (SQ-LNSs) can promote growth and prevent undernutrition. This study investigated the effects of the daily provision of SQ-LNSs and biscuits on linear growth and reduction in the incidence of stunting among infants in rural Indonesia.
A 6-month, non-randomised, controlled trial was conducted on 168 infants who received 20 g of SQ-LNSs, 3 pieces of biscuits, or no intervention. The outcome was length gain and incidence of stunting (length-age-z score (LAZ) <-2SD) during a 6-month follow-up.
After the 6-month intervention, the adjusted length gain and change in the LAZ (8.57 cm and -0.09 z-score unit, respectively) were higher in the SQLNS group than in the control (7.15 cm and -0.87 z-score unit, respectively) and biscuit groups (7.79 cm and -0.46 z-score unit, respectively; p<0.01). The rate of length gain was significantly higher in the SQ-LNS group (1.43 cm/month; 95% CI: 1.12-1.26) than in the biscuit (1.29 cm/month, 95% CI: 1.23-1.36) and control groups (1.19 cm/month, 95% CI: 1.12-1.26; p<0.01). At the end study, the incidence of stunting in SQ-LNS group was lower (1.8%) than in the biscuit group (8.5%) and control group (14.6%). In the SQ-LNS group, the relative risk (RR) of stunting was 0.35 and in the biscuit group (0.94).
SQ-LNSs improved linear growth and reducing the incidence of stunting over 6-months intervention.
儿童期发育迟缓是印度尼西亚常见的公共卫生问题。补充少量基于脂质的营养补充剂（SQ-LNSs）的辅食可促进生长并预防营养不良。本研究调查了每日提供SQ-LNSs和饼干对印度尼西亚农村地区婴儿线性生长及发育迟缓发生率降低的影响。
对168名婴儿进行了为期6个月的非随机对照试验，这些婴儿分别接受20克SQ-LNSs、3块饼干或不接受干预。观察指标为6个月随访期间的身长增长和发育迟缓发生率（身长年龄Z评分（LAZ）<-2SD）。
经过6个月的干预，SQ-LNS组调整后的身长增长和LAZ变化（分别为8.57厘米和-0.09 Z评分单位）高于对照组（分别为7.15厘米和-0.87 Z评分单位）和饼干组（分别为7.79厘米和-0.46 Z评分单位；p<0.01）。SQ-LNS组的身长增长率（1.43厘米/月；95%置信区间：1.12-1.26）显著高于饼干组（1.29厘米/月，95%置信区间：1.23-1.36）和对照组（1.19厘米/月，95%置信区间：1.12-1.26；p<0.01）。在研究结束时，SQ-LNS组的发育迟缓发生率（1.8%）低于饼干组（8.5%）和对照组（14.6%）。在SQ-LNS组，发育迟缓的相对风险（RR）为0.35，在饼干组为（0.94）。
在6个月的干预中，SQ-LNSs改善了线性生长并降低了发育迟缓的发生率。
