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[血小板减少症与妊娠]

[Thrombocytopenia and pregnancy].

作者信息

Kleine W

机构信息

Universitäts-Frauenklinik Freiburg.

出版信息

Arch Gynecol Obstet. 1989;245(1-4):829-32. doi: 10.1007/BF02417579.

DOI:10.1007/BF02417579
PMID:2802774
Abstract

Over the past 20 years, 16 pregnancies with thrombocytopenia were observed. Fourteen of these cases were afflicted with immune thrombocytopenic purpura (ITP, M, Werlhof). Antenatal treatment of the mothers (e.g., with corticosteroids) varied and is discussed. The methods of delivery were spontaneous vaginal (nine) or cesarean section (five). Except for one neonatal death (28th week of gestation), no significant hemorrhagic morbidity occurred. On the basis of this experience and the literature, an individual management of delivery for parturient patients with ITP is proposed.

摘要

在过去20年中,观察到16例妊娠合并血小板减少症的病例。其中14例患有免疫性血小板减少性紫癜(ITP,M,韦尔霍夫病)。母亲的产前治疗(如使用皮质类固醇)各不相同,并对此进行了讨论。分娩方式为自然阴道分娩(9例)或剖宫产(5例)。除1例新生儿死亡(妊娠28周)外,未发生明显的出血性并发症。基于这一经验和文献,提出了对ITP产妇进行个体化分娩管理的建议。

相似文献

1
[Thrombocytopenia and pregnancy].[血小板减少症与妊娠]
Arch Gynecol Obstet. 1989;245(1-4):829-32. doi: 10.1007/BF02417579.
2
[Pregnancy and labor in idiopathic thrombocytopenic purpura (Werlhof disease)].[特发性血小板减少性紫癜(韦尔霍夫病)中的妊娠与分娩]
Geburtshilfe Frauenheilkd. 1990 Feb;50(2):132-5. doi: 10.1055/s-2007-1026450.
3
[Etiology and clinical characteristics of pregnancy-emerged thrombocytopenia].[妊娠合并血小板减少症的病因及临床特征]
Zhonghua Fu Chan Ke Za Zhi. 2011 Nov;46(11):834-9.
4
Perinatal and neonatal aspects of maternal idiopathic thrombocytopenic purpura.母亲特发性血小板减少性紫癜的围产期和新生儿期情况
Am J Perinatol. 1984 Apr;1(3):251-8. doi: 10.1055/s-2007-1000014.
5
Low neonatal risk of thrombocytopenia in pregnancy associated with immune thrombocytopenic purpura.妊娠合并免疫性血小板减少性紫癜时新生儿血小板减少的风险较低。
Fetal Diagn Ther. 1999 Jul-Aug;14(4):216-9. doi: 10.1159/000020924.
6
[Clinical analysis of pregnancy complicated with severe thrombocytopenia].妊娠合并严重血小板减少症的临床分析
Zhonghua Fu Chan Ke Za Zhi. 2010 Jun;45(6):401-5.
7
Route of delivery for patients with immune thrombocytopenic purpura.免疫性血小板减少性紫癜患者的分娩方式
Am J Obstet Gynecol. 1984 Apr 1;148(7):901-8. doi: 10.1016/0002-9378(84)90532-5.
8
[Thrombocytopenia in newborn infants caused by autoimmune thrombocytopenic purpura in their mothers].[母亲自身免疫性血小板减少性紫癜所致新生儿血小板减少症]
Wiad Lek. 1992 Apr;45(7-8):270-4.
9
Immune thrombocytopenic purpura in pregnancy: a reappraisal of obstetric management and outcome.妊娠期免疫性血小板减少性紫癜:产科管理与结局的重新评估
J Reprod Med. 2011 Mar-Apr;56(3-4):163-8.
10
Fetal platelet counts in the obstetric management of immunologic thrombocytopenic purpura.免疫性血小板减少性紫癜产科管理中的胎儿血小板计数
Am J Obstet Gynecol. 1980 Feb 15;136(4):495-9. doi: 10.1016/0002-9378(80)90677-8.

本文引用的文献

1
Platelet counts in infants of women with autoimmune thrombocytopenia: effects of steroid administration to the mother.自身免疫性血小板减少症女性所生婴儿的血小板计数:母亲使用类固醇的影响。
N Engl J Med. 1981 Oct 15;305(16):936-9. doi: 10.1056/NEJM198110153051607.
2
Management of pregnancy in women with immune thrombocytopenic purpura.免疫性血小板减少性紫癜女性患者的妊娠管理
JAMA. 1980 Dec 19;244(24):2756-8.
3
Antiplatelet antibodies and platelet counts in pregnancies complicated by autoimmune thrombocytopenic purpura.自身免疫性血小板减少性紫癜合并妊娠的抗血小板抗体与血小板计数
Am J Obstet Gynecol. 1983 Apr 15;145(8):932-9. doi: 10.1016/0002-9378(83)90843-8.
4
Route of delivery for patients with immune thrombocytopenic purpura.免疫性血小板减少性紫癜患者的分娩方式
Am J Obstet Gynecol. 1984 Apr 1;148(7):901-8. doi: 10.1016/0002-9378(84)90532-5.
5
Management of autoimmune thrombocytopenia in pregnancy and in the neonate.
Obstet Gynecol. 1973 Apr;41(4):579-84.
6
[Idiopathic thrombocytopenic purpura and pregnancy].[特发性血小板减少性紫癜与妊娠]
Geburtshilfe Frauenheilkd. 1985 Nov;45(11):797-802. doi: 10.1055/s-2008-1036651.
7
[Thrombocytopenia in pregnancy].[妊娠期血小板减少症]
Zentralbl Gynakol. 1985;107(13):827-31.
8
Immunologic thrombocytopenia in pregnancy; use of antenatal immunoglobulin therapy: case report and review.妊娠期免疫性血小板减少症;产前免疫球蛋白治疗的应用:病例报告及文献复习
Obstet Gynecol. 1985 Sep;66(3 Suppl):41S-43S.
9
Validity of intrapartum diagnosis of fetal thrombocytopenia.
Am J Obstet Gynecol. 1987 Oct;157(4 Pt 1):864-5. doi: 10.1016/s0002-9378(87)80074-1.
10
Transplacental effect of high-dose immunoglobulin in idiopathic thrombocytopenia (ITP).大剂量免疫球蛋白在特发性血小板减少性紫癜(ITP)中的经胎盘效应。
Lancet. 1986 May 10;1(8489):1098-9. doi: 10.1016/s0140-6736(86)91366-8.