Department of Radiology, Gil Medical Center, Gachon University College of Medicine, 21, Namdong-daero 774 Beon-gil, Namdong-gu, Incheon, 21565, Republic of Korea.
Siemens Healthineers Ltd., Seoul, Republic of Korea.
Eur Radiol. 2024 Apr;34(4):2233-2243. doi: 10.1007/s00330-023-10226-w. Epub 2023 Sep 21.
We aimed to compare the image quality and focal lesion detection ability of hepatobiliary phase (HBP) images obtained using compressed sensing (CS) and controlled aliasing in parallel imaging results in higher acceleration (CAIPIRINHA) in patients with liver cirrhosis.
We retrospectively included 244 gadoxetic acid-enhanced liver MRI from 244 patients with cirrhosis obtained by two HBP images using CS and CAIPIRINHA from July 2020 to December 2020. The optimized resolution and scan time for CS-HBP and CAIPIRINHA-HBP were 0.9 × 0.9 × 1.5 mm and 15 s and 1.3 × 1.3 × 3 mm and 16 s, respectively. We compared the image quality between the two sets of images in 244 patients and focal lesion (n = 294) analyses for 112 patients.
CS-HBP showed comparable overall image quality (3.7 ± 0.9 vs. 3.6 ± 0.8, p = 0.680), superior liver edge sharpness (3.9 ± 0.6 vs. 3.6 ± 0.5, p < 0.001), and fewer respiratory motion artifacts (4.0 ± 0.7 vs. 3.8 ± 0.5, p < 0.001), but higher non-respiratory artifacts (3.4 ± 0.7 vs. 3.6 ± 0.6, p < 0.001) and subjective image noise (3.5 ± 0.8 vs. 3.6 ± 0.7, p = 0.014) than CAIPIRINHA-HBP. CS-HBP showed a higher signal-to-noise ratio in the liver than CAIPIRINHA-HBP (20.9 ± 9.0 vs. 18.9 ± 7.1, p = 0.008). The pooled sensitivity, specificity, and AUC were 90.0%, 77.5%, and 0.84 for CS-HBP and 73.5%, 82.4%, and 0.78 for CAIPIRINHA-HBP, respectively.
CS-HBP showed better focal lesion detection ability, comparable overall image quality, and fewer respiratory motion artifacts, but higher non-respiratory artifacts and noise compared to CAIPIRINHA-HBP. Thus, CS-HBP could be recommended for liver MRI in patients with cirrhosis to improve diagnostic performance.
Thin-slice CS-HBP may be useful for detecting sub-centimeter hepatocellular carcinoma in cirrhotic patients with Child-Pugh classification A while maintaining comparable subjective image quality.
• Compared with controlled aliasing in parallel imaging results in higher acceleration, compressed sensing hepatobiliary phase yielded thinner slices and shorter scan time at a higher accelerating factor. • Compressed sensing hepatobiliary phase showed comparable overall image quality, superior liver edge sharpness, and fewer respiratory motion artifacts, but higher non-respiratory artifacts and subjective image noise than controlled aliasing in parallel imaging results in higher acceleration-hepatobiliary phase. • Compressed sensing hepatobiliary phase can detect sub-centimeter hepatocellular carcinoma in cirrhotic patients with Child-Pugh classification A.
我们旨在比较使用压缩感知（CS）和并行成像结果中的受控叠加在更高加速（CAIPIRINHA）中获得的肝胆期（HBP）图像的质量和焦点病变检测能力在肝硬化患者中。
我们回顾性地纳入了 2020 年 7 月至 2020 年 12 月期间通过两种 CS 和 CAIPIRINHA 从 244 例肝硬化患者中获得的 244 例钆喷酸葡胺增强肝脏 MRI 的 HBP 图像。CS-HBP 的优化分辨率和扫描时间分别为 0.9×0.9×1.5mm 和 15s，CAIPIRINHA-HBP 的分辨率和扫描时间分别为 1.3×1.3×3mm 和 16s。我们比较了 244 例患者的两组图像的图像质量，并对 112 例患者的焦点病变（n=294）进行了分析。
CS-HBP 显示出相当的整体图像质量（3.7±0.9 与 3.6±0.8，p=0.680）、更好的肝边缘锐度（3.9±0.6 与 3.6±0.5，p<0.001）和更少的呼吸运动伪影（4.0±0.7 与 3.8±0.5，p<0.001），但更高的非呼吸伪影（3.4±0.7 与 3.6±0.6，p<0.001）和主观图像噪声（3.5±0.8 与 3.6±0.7，p=0.014），但比 CAIPIRINHA-HBP 高。CS-HBP 显示出比 CAIPIRINHA-HBP 更高的肝脏信噪比（20.9±9.0 与 18.9±7.1，p=0.008）。CS-HBP 的汇总灵敏度、特异性和 AUC 分别为 90.0%、77.5%和 0.84，CAIPIRINHA-HBP 的分别为 73.5%、82.4%和 0.78。
CS-HBP 显示出更好的焦点病变检测能力、相当的整体图像质量和更少的呼吸运动伪影，但与 CAIPIRINHA-HBP 相比，它具有更高的非呼吸伪影和噪声。因此，CS-HBP 可用于肝硬化患者的肝脏 MRI，以提高诊断性能。
在 Child-Pugh 分类为 A 的肝硬化患者中，薄切片 CS-HBP 可能有助于检测亚厘米级肝细胞癌，同时保持可比的主观图像质量。
与更高加速的并行成像结果中的受控叠加相比，压缩感知肝胆期产生更薄的切片和更短的扫描时间，同时具有更高的加速因子。
压缩感知肝胆期显示出相当的整体图像质量、更好的肝边缘锐度和更少的呼吸运动伪影，但与更高加速的并行成像结果中的受控叠加肝胆期相比，它具有更高的非呼吸伪影和主观图像噪声。
压缩感知肝胆期可检测出 Child-Pugh 分类为 A 的肝硬化患者中的亚厘米级肝细胞癌。
