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原发性肠系膜神经内分泌肿瘤内部成分由囊性变为实性:病例报告

Primary mesenteric neuroendocrine tumor that changed its internal composition from cystic to solid: a case report.

作者信息

Yasuda Akira, Kitagami Hidehiko, Kondo Yasuhiro, Nonoyama Keisuke, Watanabe Kaori, Fujihata Shiro, Miyai Hirotaka, Yamamoto Minoru, Shimizu Yasunobu, Tanaka Moritsugu

机构信息

Department of Surgery, Kariya Toyota General Hospital, 5-15, Sumiyoshi-cho, Kariya, Aichi, 448-8505, Japan.

出版信息

Clin J Gastroenterol. 2017 Feb;10(1):18-22. doi: 10.1007/s12328-016-0695-y. Epub 2016 Dec 27.

Abstract

Mesenteric neuroendocrine tumors are usually metastases originating from the small intestine; however, primary mesenteric cases are rare. We present an interesting case of a mesenteric neuroendocrine tumor that changed its internal composition from cystic to solid. A 72-year-old male visited our hospital because of epigastralgia 4 years earlier. A 25-mm tumor was recognized around the terminal duodenum on computed tomography and magnetic resonance imaging, and was diagnosed as a cystic lesion. Over the following 2 years, the tumor grew to 40 mm and its internal composition changed from cystic to solid. The lesion showed positive findings on fluorodeoxyglucose positron emission tomography. Upon laparotomy, a solid tumor was detected in the mesentery of the jejunum near the ligament of Treitz. The tumor was extracted without intestinal resection and was diagnosed as a low-grade neuroendocrine tumor after histopathological and immunohistochemical examination. One year has passed since the operation, and there has been no recurrence.

摘要

肠系膜神经内分泌肿瘤通常是源自小肠的转移瘤;然而,原发性肠系膜病例较为罕见。我们报告一例有趣的肠系膜神经内分泌肿瘤病例,其内部成分从囊性转变为实性。一名72岁男性于4年前因上腹部疼痛前来我院就诊。计算机断层扫描和磁共振成像显示十二指肠末端周围有一个25毫米的肿瘤,诊断为囊性病变。在接下来的2年里,肿瘤长至40毫米,其内部成分从囊性转变为实性。该病变在氟脱氧葡萄糖正电子发射断层扫描中显示阳性结果。剖腹探查时,在Treitz韧带附近的空肠系膜中发现一个实性肿瘤。未进行肠切除就将肿瘤摘除,经组织病理学和免疫组织化学检查后诊断为低级别神经内分泌肿瘤。手术已过去一年,未出现复发情况。

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