Choline and acetylcholine: what a difference an acetate makes!
作者信息
Gibb Alasdair J
机构信息
Department of Neuroscience, Physiology and Pharmacology, University College London, London, WC1E 6BT, UK.
出版信息
J Physiol. 2017 Feb 15;595(4):1021-1022. doi: 10.1113/JP273666. Epub 2017 Jan 25.
Abstract
摘要
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Choline and acetylcholine: what a difference an acetate makes!胆碱与乙酰胆碱：一个乙酸根竟能造成如此大的差异！
J Physiol. 2017 Feb 15;595(4):1021-1022. doi: 10.1113/JP273666. Epub 2017 Jan 25.
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3
Studies on presynaptic cholinergic mechanisms using analogues of choline and acetate.使用胆碱和乙酸盐类似物对突触前胆碱能机制的研究。
J Physiol (Paris). 1982;78(4):454-60.
4
[PHARMACOLOGICAL CHARACTERISTICS OF SUBSTANCES INHIBITING ACETYLCHOLINE SYNTHESIS IN THE BODY].[体内抑制乙酰胆碱合成物质的药理学特性]
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[Effect of glutamic acid on cholinergic excitation in the neuro-muscular synapses].[谷氨酸对神经肌肉突触中胆碱能兴奋的影响]
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Acetylcholinesterase at the myoneural junction: cytochemical ultrastructure and some biochemical considerations.神经肌肉接头处的乙酰胆碱酯酶：细胞化学超微结构及一些生化方面的考量
J Histochem Cytochem. 1972 Oct;20(10):771-92. doi: 10.1177/20.10.771.
7
Kinetics of procaine-acetyl-choline antagonism.普鲁卡因 - 乙酰胆碱拮抗作用的动力学
Am J Physiol. 1963 Jan;204:73-6. doi: 10.1152/ajplegacy.1963.204.1.73.
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Modulation of transmitter synthesis and release in cholinergic terminals.胆碱能终末中递质合成与释放的调节。
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Studies in neuromuscular function. III. Stimulating and depressant effects of acetylcholine and choline in normal subjects.神经肌肉功能研究。III. 乙酰胆碱和胆碱对正常受试者的刺激和抑制作用。
Bull Johns Hopkins Hosp. 1956 Sep;99(3):136-52.
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P2X receptors supply extracellular choline as a substrate for acetylcholine synthesis.P2X 受体提供细胞外胆碱作为乙酰胆碱合成的底物。
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本文引用的文献
1
Molecular recognition at cholinergic synapses: acetylcholine versus choline.胆碱能突触处的分子识别：乙酰胆碱与胆碱
J Physiol. 2017 Feb 15;595(4):1253-1261. doi: 10.1113/JP273291. Epub 2016 Dec 12.
2
Structural correlates of affinity in fetal versus adult endplate nicotinic receptors.胎儿与成人终板烟碱型受体亲和力的结构关联
Nat Commun. 2016 Apr 22;7:11352. doi: 10.1038/ncomms11352.
3
The intrinsic energy of the gating isomerization of a neuromuscular acetylcholine receptor channel.神经肌肉型乙酰胆碱受体通道门控异构化的内禀能量。
J Gen Physiol. 2012 May;139(5):349-58. doi: 10.1085/jgp.201110752.
4
Nicotine and carbamylcholine binding to nicotinic acetylcholine receptors as studied in AChBP crystal structures.在烟碱型乙酰胆碱结合蛋白晶体结构中研究尼古丁和氨甲酰胆碱与烟碱型乙酰胆碱受体的结合情况。
Neuron. 2004 Mar 25;41(6):907-14. doi: 10.1016/s0896-6273(04)00115-1.
5
ON THE NATURE OF ALLOSTERIC TRANSITIONS: A PLAUSIBLE MODEL.关于别构转变的本质：一个合理的模型。
J Mol Biol. 1965 May;12:88-118. doi: 10.1016/s0022-2836(65)80285-6.
6
Spontaneous openings of the acetylcholine receptor channel.乙酰胆碱受体通道的自发开放。
Proc Natl Acad Sci U S A. 1984 Jun;81(12):3901-4. doi: 10.1073/pnas.81.12.3901.
7
On the application of "a plausible model" of allosteric proteins to the receptor for acetylcholine.关于变构蛋白“合理模型”在乙酰胆碱受体上的应用。
J Theor Biol. 1967 Aug;16(2):306-20. doi: 10.1016/0022-5193(67)90011-2.
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