Clinic of Conservative Dentistry and Periodontology, University of Kiel, Kiel, Germany.
Institute of Medical Statistics, Computer Sciences and Documentation, Jena University Hospital, Jena, Germany.
J Clin Periodontol. 2017 Feb;44(2):169-177. doi: 10.1111/jcpe.12680. Epub 2017 Jan 19.
The longitudinal study assessed the risk of tooth loss under a non-regenerative treatment regimen and aimed to identify prognostic factors for tooth loss.
Three hundred and fifteen patients (8009 teeth) were examined before (T0) and after active periodontal therapy (APT, T1) as well as after (mean ± SD) 18 ± 6 years of supportive periodontal therapy (SPT, T2). Descriptive statistics and a Cox proportional hazards shared-frailty model were applied.
Overall, 351 and 816 teeth were lost during APT and SPT, respectively, with 0.15 ± 0.17 teeth being lost per patient and year. Seventy-two percentage patients lost 0-3, 24% 4-9 and 4% ≥10 teeth. The proportion of teeth with probing-pocket depths (PPD) >6 mm was 17.2% (T0), 1.6% (T1) and remained stable at 1.7% up to T2. Tooth loss during SPT was significantly increased in older patients [HR (95% CI): 1.04 (1.01-1.07) per year] and smokers [2.62 (1.34-5.14)], with each mm of PPD [1.35 (1.17-1.56)], in multirooted compared with single-rooted teeth [1.86 (1.36-2.56)] and teeth with bone loss [BL; HR up to 23.6 (12.1-45.6) for BL > 70%].
The risk of tooth loss was generally low under the provided non-regenerative treatment regimen; a minority of patients were responsible for the majority of teeth lost during SPT.
本纵向研究评估了在非再生治疗方案下牙齿缺失的风险，并旨在确定牙齿缺失的预后因素。
315 名患者（8009 颗牙）在牙周基础治疗（APT，T1）前（T0）、后以及牙周支持治疗（SPT，T2）后（平均±SD 18±6 年）进行了检查。采用描述性统计和 Cox 比例风险共享脆弱性模型进行分析。
总体而言，APT 和 SPT 期间分别有 351 和 816 颗牙丢失，每位患者和每年分别有 0.15±0.17 颗牙丢失。72%的患者丢失 0-3 颗牙，24%丢失 4-9 颗牙，4%丢失≥10 颗牙。T0 时，探诊袋深度（PPD）>6mm 的牙齿比例为 17.2%，T1 时为 1.6%，直到 T2 时仍稳定在 1.7%。SPT 期间的牙齿丢失在老年患者中显著增加[风险比（95%可信区间）：每年增加 1.04（1.01-1.07）]和吸烟者[2.62（1.34-5.14）]，每增加 1mm 的 PPD[1.35（1.17-1.56）]，多根牙比单根牙[1.86（1.36-2.56）]和有骨丧失（BL）的牙齿[风险比高达 23.6（12.1-45.6）]。
在提供的非再生治疗方案下，牙齿缺失的风险通常较低；少数患者对 SPT 期间大多数牙齿的丢失负责。
