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巴西库里蒂巴一家血液中心的血液废弃率。十年研究。

Blood discard rate in a blood center in Curitiba - Brazil. Ten years of study.

作者信息

Monich Aline G, Dantas Tiago W, Fávero Karla B, Almeida Paulo T R, Maluf Eliane C, Capeletto Carolina De M, Nisihara Renato M

机构信息

Departamento de Medicina, Faculdade Evangélica do Paraná, Curitiba, Paraná, Brazil.

Instituto Paranaense de Hemoterapia e Hematologia Ltda, Curitiba, Paraná, Brazil.

出版信息

Transfus Apher Sci. 2017 Apr;56(2):130-134. doi: 10.1016/j.transci.2016.10.007. Epub 2016 Oct 25.

Abstract

INTRODUCTION

Development of technologies to reduce transfusion risks of infectious diseases is a major characteristic of hemotherapy. Thus, each donation undergoes clinical and serological screening tests to ensure the donated blood do not offer risks to the receiver.

OBJECTIVE

Evaluate the prevalence of positive serology in blood donations rejected by Hemobanco (Curitiba - PR) in the period ranging from January 2003 to December 2012.

METHODOLOGY

During the period studied, we observed the total number of donations and its division according to gender. We also analyzed the number of rejected donations due to seropositivity, considering the diseases investigated routinely in blood banks in Brazil, and the frequency of discards according to age groups.

RESULTS

Within the period studied, 399,280 donations were performed. 62.0% donors were male. Comparing 2003 to 2012, we noticed a significant decrease of discards, from 10.2% to 5.0%, respectively. There was a reduction of seropositivity for HIV, HBsAg and anti-HBc and an increase for Chagas Disease, hepatitis C, syphilis and HTLV. The age group with the highest prevalence for discards changed: it used to be the 40-59 years old group in 2003, and became the 20-39 years old group in 2012.

CONCLUSION

There was an increase in the number of donations in Hemobanco and a decrease in total discards due to seropositive donations. Most donors were male. The most prevalent cause of discards only amongst seropositive donation discards is seropositivity for anti-HBc. There was a significant increase of donors aged between 20 and 39 years old.

摘要

引言

开发降低输血感染疾病风险的技术是血液疗法的一个主要特征。因此,每次献血都要进行临床和血清学筛查测试,以确保所献血液不会给受血者带来风险。

目的

评估2003年1月至2012年12月期间库里蒂巴血液中心(巴拉那州)拒收的献血中血清学阳性的患病率。

方法

在研究期间,我们观察了献血总数及其按性别划分的情况。我们还分析了因血清学阳性而被拒收的献血数量,考虑了巴西血库常规检测的疾病,以及按年龄组划分的废弃率。

结果

在研究期间,共进行了399,280次献血。62.0%的献血者为男性。比较2003年至2012年,我们注意到废弃率显著下降,分别从10.2%降至5.0%。艾滋病毒、乙肝表面抗原和抗-HBc的血清学阳性率有所下降,而恰加斯病、丙型肝炎、梅毒和人类嗜T淋巴细胞病毒的血清学阳性率有所上升。废弃率最高的年龄组发生了变化:2003年是40 - 59岁年龄组,2012年变为20 - 39岁年龄组。

结论

库里蒂巴血液中心的献血数量有所增加,因血清学阳性而被废弃的总数有所减少。大多数献血者为男性。在仅因血清学阳性而被废弃的献血中,最常见的废弃原因是抗-HBc血清学阳性。20至39岁的献血者数量显著增加。

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