Mackenzie Evangelical School of Medicine of Paraná - Curitiba (PR), Brazil.
Universidade Federal do Paraná, Department of Medical Clinic - Curitiba (PR), Brazil.
Rev Assoc Med Bras (1992). 2024 Sep 2;70(8):e20240452. doi: 10.1590/1806-9282.20240452. eCollection 2024.
Routine screening for viral infections at blood donation is important to avoid transfusion-transmitted infections. It also offers an opportunity to detect an asymptomatic infection.
To study changes in serology positivity for viral infections (B and C hepatitis, HTLV-1/2, and HIV) at blood donation in a blood bank from Southern Brazil, comparing two periods of 5 years: the period from 2013 to 2017 with the period from 2018 to 2022. In addition, data on the donor fidelity rate during the studied period were sought.
Retrospective study using data from 2013 to 2022 from a single blood center electronic database from Curitiba, Southern Brazil.
A significant drop in positive serology for all studied viruses was observed: highest in HIV (OR=0.39; 95% CI=0.27-0.57) and lowest in total anti HBc (0.56; 95 CI=0.50-0.63). Anti HBc serology became more commonly seen in women in the period of 2018-2022 when compared to men. No changes in the distribution of positive serology according to donors' ages were observed. Loyalty rates had a median of 70%, with the lowest being 60% in 2013, while the highest was 73% in 2018 and 2022.
A significant reduction in discarded blood bags due to viral serology was observed when the period of 2013-2017 was compared to 2018-2022 on this blood bank; the highest reduction was observed in HIV serology and the lowest in HBc serology, which became more common in women in the second period. High rates of donor fidelity were observed during the period studied.
在献血时进行常规病毒感染筛查对于避免输血传播感染很重要，同时也为发现无症状感染提供了机会。
研究巴西南部一家血库在两个 5 年期间（2013 年至 2017 年和 2018 年至 2022 年）献血者病毒感染（乙型和丙型肝炎、HTLV-1/2 和 HIV）血清学阳性率的变化，并寻找研究期间供者忠实率的数据。
使用巴西南部库里蒂巴的一个单一血液中心电子数据库中 2013 年至 2022 年的数据进行回顾性研究。
所有研究病毒的阳性血清学均显著下降：HIV 最高（OR=0.39；95%CI=0.27-0.57），总抗 HBc 最低（0.56；95%CI=0.50-0.63）。与男性相比，2018-2022 年期间，抗 HBc 血清学在女性中更为常见。阳性血清学的分布根据供者年龄没有变化。忠实率中位数为 70%，最低为 2013 年的 60%，最高为 2018 年和 2022 年的 73%。
与 2013-2017 年相比，2018-2022 年该血库因病毒血清学而丢弃的血袋数量显著减少；HIV 血清学的减少幅度最大，HBc 血清学的减少幅度最小，而在第二个时期，HBc 血清学在女性中更为常见。在研究期间观察到供者忠实率很高。
