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[实验性全身热疗条件下肠系膜淋巴结淋巴组织的显微解剖结构和细胞构筑学]

[Microanatomical organization and cytoarchitectonics of lymphoid tissue in the mesenteric lymph nodes under conditions of experimental total hyperthermia].

作者信息

Zaĭko T M, Grigor'ev V N

出版信息

Arkh Anat Gistol Embriol. 1989 Jun;96(6):60-5.

PMID:2803018
Abstract

Microanatomical organization and cell composition of the rat mesenteric lymph nodes have been studied under conditions of experimental total hyperthermia. Possibilities of the compensatory-adaptive reactions of the lymphoid tissue have been determined. Disturbances of microhemo-++- and lymphocirculation in the lymph nodes in different time after hyperthermia are accompanied with accumulation of mast cells and eosinophils in various zones of the node; they normalize certain physiological parameters of microcirculation and permeability of the metabolic microvessel walls. In 30 days after a single total overheating of the rat organism, the microanatomical organization changes in the lymph nodes investigated are manifested as atrophy of B-dependent zones and further volumetric increase of the paracortical zone. Therefore, it is possible to think about a decreasing intensity of the humoral immunity and increasing intensity of the cellular one.

摘要

在实验性全身热疗条件下,对大鼠肠系膜淋巴结的微观解剖结构和细胞组成进行了研究。确定了淋巴组织代偿性适应反应的可能性。热疗后不同时间淋巴结内微循环和淋巴循环的紊乱伴随着肥大细胞和嗜酸性粒细胞在淋巴结不同区域的积聚;它们使微循环的某些生理参数和代谢性微血管壁的通透性恢复正常。在大鼠机体单次全身过热30天后,所研究淋巴结的微观解剖结构变化表现为B细胞依赖区萎缩,副皮质区进一步体积增大。因此,可以认为体液免疫强度降低,细胞免疫强度增加。

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