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[嗜酸性肾肿瘤的形态学与鉴别诊断]

[Morphology and differential diagnosis of oncocytic kidney tumors].

作者信息

Vlodavskiĭ E A

出版信息

Arkh Patol. 1989;51(7):25-30.

PMID:2803040
Abstract

5 oncocytomas and 3 oncocytic carcinomas were studied morphologically, morphometrically, cytophotometrically, histochemically and ultrastructurally. Oncocytic carcinoma is characterized by the presence of necrotic foci, pronounced cell and nuclear polymorphism, invasive growth. Significantly higher degree of the nucleus size variability is found in the oncocytic carcinoma (as compared to oncocytoma). Anomalies of DNA content in the form of aneuploidy and polyploidy are found cytophotometrically in all oncocytic carcinomas but in 2 out of 5 cases oncocytomas only.

摘要

对5例嗜酸细胞瘤和3例嗜酸细胞癌进行了形态学、形态测量学、细胞光度学、组织化学和超微结构研究。嗜酸细胞癌的特征为存在坏死灶、明显的细胞和核多形性以及浸润性生长。在嗜酸细胞癌中发现细胞核大小变异性程度明显更高(与嗜酸细胞瘤相比)。通过细胞光度学在所有嗜酸细胞癌中均发现非整倍体和多倍体形式的DNA含量异常,但仅在5例嗜酸细胞瘤中的2例中发现。

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