Wolford E, Pesonen A-K, Heinonen K, Lahti M, Pyhälä R, Lahti J, Hovi P, Strang-Karlsson S, Eriksson J G, Andersson S, Järvenpää A-L, Kajantie E, Räikkönen K
1Institute of Behavioral Sciences,University of Helsinki,Helsinki,Finland.
5Children's Hospital,University of Helsinki and Helsinki University Hospital,Helsinki,Finland.
J Dev Orig Health Dis. 2017 Apr;8(2):161-167. doi: 10.1017/S2040174416000738. Epub 2016 Dec 29.
Visual processing problems may be one underlying factor for cognitive impairments related to autism spectrum disorders (ASDs). We examined associations between ASD-traits (Autism-Spectrum Quotient) and visual processing performance (Rey-Osterrieth Complex Figure Test; Block Design task of the Wechsler Adult Intelligence Scale-III) in young adults (mean age=25.0, s.d.=2.1 years) born preterm at very low birth weight (VLBW; <1500 g) (n=101) or at term (n=104). A higher level of ASD-traits was associated with slower global visual processing speed among the preterm VLBW, but not among the term-born group (P<0.04 for interaction). Our findings suggest that the associations between ASD-traits and visual processing may be restricted to individuals born preterm, and related specifically to global, not local visual processing. Our findings point to cumulative social and neurocognitive problems in those born preterm at VLBW.
视觉处理问题可能是与自闭症谱系障碍（ASD）相关的认知障碍的一个潜在因素。我们研究了低出生体重（VLBW；<1500克）早产（n=101）或足月出生（n=104）的年轻成年人（平均年龄=25.0，标准差=2.1岁）的ASD特征（自闭症谱系商数）与视觉处理能力（雷-奥斯特里茨复杂图形测试；韦氏成人智力量表第三版的积木设计任务）之间的关联。在早产VLBW组中，较高水平的ASD特征与较慢的整体视觉处理速度相关，但足月出生组则不然（交互作用P<0.04）。我们的研究结果表明，ASD特征与视觉处理之间的关联可能仅限于早产个体，并且具体与整体而非局部视觉处理相关。我们的研究结果指出了低出生体重早产个体存在累积的社会和神经认知问题。
