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即时检测血红蛋白/血细胞比容设备及自体血回输对减少围手术期异体输血的影响

Effect of Point-of-care Hemoglobin/Hematocrit Devices and Autologous Blood Salvage on Reduction of Perioperative Allogeneic Blood Transfusion.

作者信息

Chen Wei-Yun, Yu Xue-Rong, Zhang Jiao, Yuan Qing, Huang Yu-Guang

出版信息

Chin Med Sci J. 2016 Jun 20;31(2):83-88. doi: 10.1016/s1001-9294(16)30030-x.

Abstract

Objective To evaluate the effect of point-of-care hemoglobin/hematocrit (POC HGB/HCT) devices and intraoperative blood salvage on the amount of perioperative allogeneic blood transfusion and blood conservation in clinical practice.Methods A total of 46 378 medical records of 22 selected hospitals were reviewed. The volume of allogeneic red blood cell and plasma, number of patients transfused, number of intraoperative autologous blood salvage, total volume of autologous blood transfusion, and amount of surgery in the year of 2011 and 2013 were tracked. Paired t-test was used in intra-group comparison, while t-test of two isolated samples carried out in inter-group comparison. P<0.05 was defined as statistically significant difference.Results In the hospitals where POC HGB/HCT device was used (n=9), the average allogeneic blood transfusion volume per 100 surgical cases in 2013 was significantly lower than that in 2011 (39.86±20.20 vs. 30.49±17.50 Units, t=3.522, P=0.008). In the hospitals without POC HGB/HCT meter, the index was not significantly different between 2013 and 2011. The average allogeneic blood transfusion volume was significantly reduced in 2013 than in 2011 in the hospitals where intraoperative autologous blood salvage ratio [autologous transfusion volume/(autologous transfusion volume+allogeneic transfusion volume)] was increased (n=12, t=2.290, P=0.042). No significant difference of the above index was found in the hospitals whose autologous transfusion ratio did not grow.Conclusion Intraoperative usage of POC HGB/HCT devices and increasing autologous transfusion ratio could reduce perioperative allogeneic blood transfusion.

摘要

目的 评估即时检测血红蛋白/血细胞比容(POC HGB/HCT)设备及术中血液回收对临床实践中围手术期异体输血及血液保护量的影响。方法 回顾了22家选定医院的46378份病历。追踪了2011年和2013年异体红细胞和血浆的输注量、输血患者数量、术中自体血回收量、自体输血总量及手术量。组内比较采用配对t检验,组间比较采用两独立样本t检验。P<0.05为差异有统计学意义。结果 使用POC HGB/HCT设备的医院(n=9),2013年每100例手术病例的平均异体输血总量显著低于2011年(39.86±20.20单位 vs. 30.49±17.50单位,t=3.522,P=0.008)。未使用POC HGB/HCT设备的医院,该指标在2013年和2011年之间无显著差异。在术中自体血回收比例[自体输血量/(自体输血量+异体输血量)]增加的医院(n=12),2013年的平均异体输血总量较2011年显著减少(t=2.290,P=0.042)。自体输血比例未增加的医院,上述指标无显著差异。结论 术中使用POC HGB/HCT设备及提高自体输血比例可减少围手术期异体输血。

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