Yong E L, Wong P C, Kumar A, Wong Y C, Goh H H, Hagglund L, Ratnam S
Department of Obstetrics and Gynaecology, National University Hospital, Singapore.
Aust N Z J Obstet Gynaecol. 1989 May;29(2):155-60. doi: 10.1111/j.1479-828x.1989.tb01707.x.
A new urine luteinizing hormone (LH) kit, First Response (Tambrands Inc., Palmer, MA) was compared with basal body temperature (BBT), cervical mucus scoring and abdominal ultrasound follicular scanning in their ability to predict ovulation to within 2 days of the serum LH peak. BBT was kept daily. From day 10 daily ultrasound scanning and cervical mucus examination were performed and serum oestradiol, luteinizing hormone, follicular stimulating hormone and progesterone were assayed. First Response was significantly more accurate than BBT and cervical mucus when compared in their ability to predict ovulation to within 2 days of the LH peak (p less than 0.05). First Response pinpointed 93% (27/29) of the ovulatory cycles compared to 72% (18/25) and 61% (19/31) for BBT and cervical mucus respectively. It was better but not significantly so against abdominal ultrasound which predicted 77% (24/31). The implications of this finding and the value of the other simple office tests in clinical practice are discussed.
一种新的尿促黄体生成素（LH）检测试剂盒，即First Response（坦布兰兹公司，马萨诸塞州帕尔默），与基础体温（BBT）、宫颈黏液评分及腹部超声卵泡扫描在预测排卵时间至血清LH峰值的2天内的能力方面进行了比较。每天记录基础体温。从第10天开始，每天进行超声扫描和宫颈黏液检查，并检测血清雌二醇、促黄体生成素、促卵泡生成素和孕酮。在预测排卵时间至LH峰值的2天内的能力方面进行比较时，First Response检测试剂盒比基础体温和宫颈黏液评分显著更准确（p<0.05）。First Response检测试剂盒能准确判断93%（27/29）的排卵周期，相比之下，基础体温和宫颈黏液评分分别为72%（18/25）和61%（19/31）。与预测准确率为77%（24/31）的腹部超声相比，它的效果更好，但差异不显著。本文讨论了这一发现的意义以及其他简单门诊检查在临床实践中的价值。
